RAB3IL1 and EXOC8

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		RAB3IL1	EXOC8
Description		RAB3A interacting protein like 1	exocyst complex component 8
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Projection Perinuclear Region Of Cytoplasm Cell Periphery
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding
	Biological Process	Protein Transport	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Endosome Organization Intracellular Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Membrane Fission Vesicle Tethering Involved In Exocytosis
Pathways		RAB GEFs exchange GTP for GDP on RABs	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Metabolite levels ( 23823483) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Reticulocyte fraction of red cells ( 32888494)	Hemoglobin concentration ( 27863252)
Interacting Genes		27 interacting genes: C14orf119 C2orf68 CCDC57 COG6 CTDSP1 CYSRT1 EXOC8 FHL5 HSF2BP IP6K1 KRT34 KRT40 KRTAP6-3 MAP3K1 MTUS2 NBPF19 NOTCH2NLA NUDT18 PSMA3 RAB11A RAB3A RAB3IP RAB8A SATB2 STX1A TIGD7 TTC7B	88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4
Entrez ID		5866	149371
HPRD ID		10181	09943
Ensembl ID		ENSG00000167994	ENSG00000116903
Uniprot IDs		Q8TBN0	Q8IYI6
PDB IDs		4LI0
Enriched GO Terms of Interacting Partners?		Membrane Docking Organelle Localization By Membrane Tethering Vesicle Docking Involved In Exocytosis Myosin V Binding Vesicle Docking Vesicle-mediated Transport In Synapse Exocytosis Vesicle-mediated Transport To The Plasma Membrane Organelle Localization Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Vesicle Organization Regulation Of Neuronal Synaptic Plasticity Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Golgi To Plasma Membrane Transport Localization Within Membrane Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Secretion By Cell Post-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Organization Synaptic Vesicle Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Secretion Protein Transport Protein Localization To Membrane Calcium-ion Regulated Exocytosis Regulation Of Presynaptic Dense Core Granule Exocytosis Synaptic Vesicle Exocytosis Evoked Neurotransmitter Secretion Synaptic Vesicle Membrane Myosin Head/neck Binding Synaptic Vesicle Endosomal Processing Golgi Vesicle Transport 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Regulation Of Calcium Ion-dependent Exocytosis Intermediate Filament Vesicle-mediated Transport Centriole Golgi Vesicle Fusion To Target Membrane Receptor Localization To Synapse Insulin Secretion	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Protein Binding Supramolecular Fiber Organization Intermediate Filament Organelle Organization Structural Molecule Activity Negative Regulation Of Viral Transcription Cytoskeleton Regulation Of Viral Transcription Regulation Of Post-translational Protein Modification Regulation Of Protein Autoubiquitination Molecular Adaptor Activity Cytoskeleton Organization Identical Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity Cellular Localization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Lysosome Size BORC Complex Post-mRNA Release Spliceosomal Complex Gamma-tubulin Binding Autophagosome Epidermis Development
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