MOB3B and LATS2

Number of citations of the paper that reports this interaction (PMID 19739119)
11

Data Source:
BioGRID (pull down)

		MOB3B	LATS2
Gene Name		MOB kinase activator 3B	large tumor suppressor kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Hormone-mediated Signaling Pathway Keratinocyte Differentiation Cellular Protein Localization Hippo Signaling Intracellular Signal Transduction Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Organ Growth Cell Division Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Urinary symptoms in response to radiotherapy in prostate cancer ( 23376709)
Protein-Protein Interactions		5 interactors: LATS1 LATS2 MAPK14 NT5C2 PPBP	19 interactors: ABL1 AJUBA AMOT AURKB CDK2 CDKN1A CHEK1 CHEK2 CTNNB1 DYRK1A MOB3A MOB3B MOB3C MOB4 SNAI1 STK3 TAZ YAP1 YWHAG
Entrez ID		79817	26524
HPRD ID		14728	07277
Ensembl ID		ENSG00000120162	ENSG00000150457
Uniprot IDs		Q86TA1	Q9NRM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Hippo Signaling Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Wnt Signaling Pathway Keratinocyte Differentiation Phosphorylation Cellular Response To Organic Substance Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity P38MAPK Cascade Regulation Of Protein Kinase Activity Negative Regulation Of Protein Serine/threonine Kinase Activity Epidermal Cell Differentiation Hormone-mediated Signaling Pathway Regulation Of Kinase Activity Response To Organic Substance Platelet Activation Cell Cycle Process Negative Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Skin Development Negative Regulation Of Signal Transduction Negative Regulation Of Kinase Activity Positive Regulation Of Brown Fat Cell Differentiation Myoblast Differentiation Involved In Skeletal Muscle Regeneration Phosphate-containing Compound Metabolic Process Negative Regulation Of Signaling Regulation Of Brown Fat Cell Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Epidermis Development Regulation Of Phosphorylation Negative Regulation Of Transferase Activity Protein Phosphorylation Cell Cycle Mitotic Nuclear Division Response To Lipopolysaccharide Negative Regulation Of Protein Phosphorylation Response To Molecule Of Bacterial Origin 3'-UTR-mediated MRNA Stabilization Regulation Of Phosphorus Metabolic Process Stress-induced Premature Senescence Negative Regulation Of Phosphorylation Blood Coagulation Cell Division Hemostasis Adenosine Metabolic Process Tissue Development Negative Regulation Of Cell Cycle	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Cycle Hippo Signaling Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Mitotic Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Cell Cycle Phase Transition DNA Damage Induced Protein Phosphorylation Positive Regulation Of Stem Cell Differentiation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Developmental Process Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Nephron Tubule Epithelial Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Mitotic Cell Cycle Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Protein Autophosphorylation Cell Cycle Checkpoint Negative Regulation Of Signaling Negative Regulation Of Kinase Activity Regulation Of Metabolic Process Regulation Of Gene Expression Signal Transduction In Response To DNA Damage Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Cell Cycle Process Protein Phosphorylation Phosphorylation Intracellular Signal Transduction Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Regulation Of Response To DNA Damage Stimulus Histone Phosphorylation Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Proliferation Cellular Response To Radiation Apoptotic Signaling Pathway
Tagcloud ?			address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Difference) ?			address approach bioinformatics carried challenging contribute damage discovery efficiently especially genome hlats1 lats1 mutations numerous opportunities powerful predicted projects putative question regulators silico sort support suppressor suppressors understood unprecedented
Tagcloud (Intersection) ?