PTCD2 and TRIM32

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTCD2	TRIM32
Gene Name		pentatricopeptide repeat domain 2	tripartite motif containing 32
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament
	Molecular Function	Poly(A) RNA Binding	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity
	Biological Process	Kidney Development Liver Development MRNA Processing Mitochondrion Organization Muscle Fiber Development Regulation Of MRNA Processing Ventricular Cardiac Muscle Tissue Morphogenesis	Protein Polyubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Cell Motility
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Regulation of innate immune responses to cytosolic DNA Cytosolic sensors of pathogen-associated DNA Class I MHC mediated antigen processing & presentation Innate Immune System Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: MID2 TRIM32	36 interactors: ABI2 ATXN1 CLIP4 DTNBP1 GLIS2 IRAK1 KCTD9 MID2 MYCN PDE9A PIAS3 PIAS4 PTCD2 PTPN11 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP SYT6 TMEM173 TOP1 TRIM23 TRIM27 TRIM5 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2U UBQLN1 UBQLN4 VPS11 XIAP
Entrez ID		79810	22954
HPRD ID		15193	03797
Ensembl ID		ENSG00000049883	ENSG00000119401
Uniprot IDs		B3KPU6 Q8WV60	Q13049
PDB IDs			2CT2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Viral Transcription Negative Regulation Of Viral Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Viral Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Localization To Microtubule Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Locomotion Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Viral Entry Into Host Cell Regulation Of Viral Entry Into Host Cell Protein Localization To Cytoskeleton Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Signal Transduction Negative Regulation Of Fibroblast Proliferation Immune Response Negative Regulation Of Gene Expression Defense Response Negative Regulation Of Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Type I Interferon Production Negative Regulation Of Cellular Metabolic Process Regulation Of Fibroblast Proliferation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Immune System Process Regulation Of Type I Interferon Production Positive Regulation Of Cell Growth Fat Cell Differentiation Response To Tumor Necrosis Factor Regulation Of Response To DNA Damage Stimulus Response To UV Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Protein Polyubiquitination Regulation Of Signaling Positive Regulation Of Protein Catabolic Process Positive Regulation Of Growth Cellular Protein Modification Process Negative Regulation Of Locomotion Negative Regulation Of Apoptotic Signaling Pathway	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Protein K48-linked Ubiquitination Regulation Of Innate Immune Response Cellular Protein Modification Process Activation Of Innate Immune Response Protein K63-linked Ubiquitination Positive Regulation Of Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Metabolic Process Cellular Response To Oxygen Levels Cellular Protein Metabolic Process Regulation Of Immune System Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response Innate Immune Response-activating Signal Transduction Negative Regulation Of Viral Release From Host Cell TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Response To Stimulus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Viral Release From Host Cell Protein K11-linked Ubiquitination Response To Stress Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Regulation Of Gene Expression Proteasomal Protein Catabolic Process Protein Metabolic Process ISG15-protein Conjugation Immune Response-regulating Signaling Pathway Immune Response Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Response To Stimulus Cellular Protein Catabolic Process Regulation Of RNA Metabolic Process
Tagcloud ?			arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Difference) ?			arrest binds e3 element ensure impairing interacts largely ligase maintaining modifications negatively oncogenic overexpressed p53 preventing promotes proper regulator responsive senescence stress tightly transcriptionally translational tumorigenesis turn ubiquitin ubiquitination
Tagcloud (Intersection) ?