CTNNBIP1

Gene Name		catenin, beta interacting protein 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex
	Molecular Function	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding
	Biological Process	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation
Pathways		misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: BEND5 CTNNA2 CTNNB1 EMD INCA1 JUP KRTAP10-3 KRTAP10-7 REL TCF7L2 USHBP1
Entrez ID		56998
HPRD ID		09677
Ensembl ID		ENSG00000178585
Uniprot IDs		Q9NSA3
PDB IDs		1LUJ 1M1E 1T08
Enriched GO Terms of Interacting Partners?		Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Indole-3-methanol Regulation Of Wnt Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Muscle Structure Development Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Protein Export From Nucleus Genitalia Morphogenesis Positive Regulation Of Signal Transduction Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Fate Specification Regulation Of Signal Transduction Regulation Of Cell Proliferation Regulation Of Nucleocytoplasmic Transport Skin Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Signaling Positive Regulation Of Intracellular Transport Regulation Of Protein Export From Nucleus Regulation Of Protein Localization Regulation Of Cell Fate Commitment Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Intracellular Protein Transport Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Epithelial Cell-cell Adhesion Regulation Of Oligodendrocyte Differentiation Myoblast Differentiation Adherens Junction Assembly Muscle Cell Differentiation Regulation Of Myelination Positive Regulation Of Protein Transport Positive Regulation Of Stem Cell Differentiation Genitalia Development Regulation Of Cellular Localization Regulation Of Epithelial To Mesenchymal Transition Digestive Tract Morphogenesis Regulation Of Glial Cell Differentiation Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Adherens Junction Organization Response To Organic Substance Canonical Wnt Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Pancreas Development Single Organismal Cell-cell Adhesion Regulation Of Fibroblast Proliferation Regulation Of Gliogenesis
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