HMBOX1 and DYNLL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HMBOX1	DYNLL2
Gene Name		homeobox containing 1	dynein, light chain, LC8-type 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Centrosome Cytosol Microtubule Plasma Membrane Membrane Myosin Complex Dynein Complex Primary Cilium Ciliary Tip
	Molecular Function	DNA Binding Protein Binding	Motor Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Transport Apoptotic Process Organelle Organization Microtubule-based Process Synaptic Target Recognition Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Organelle biogenesis and maintenance MHC class II antigen presentation Programmed Cell Death Activation of BH3-only proteins Assembly of the primary cilium Intraflagellar transport Adaptive Immune System Intrinsic Pathway for Apoptosis Activation of BMF and translocation to mitochondria
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		48 interactors: AEBP2 APP ASB7 ATP5O BYSL C20orf195 C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM206A FAM74A4 FARS2 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587	20 interactors: BCL2L11 BMF C12orf40 CCDC36 DLGAP1 DNAL4 DYNC1I1 EWSR1 GPHN GPRIN2 HMBOX1 HOMER3 MEOX2 MORN3 MYO5A PAK1 RASGRP3 SECISBP2L THAP10 XIAP
Entrez ID		79618	140735
HPRD ID		07964	06489
Ensembl ID		ENSG00000147421
Uniprot IDs		D3DSU2 Q6NT76	Q96FJ2
PDB IDs		2CUF 4J19	2XQQ 3P8M
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Chromatin Organization Biosynthetic Process Chromatin Modification Cellular Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Chromosome Organization Fatty Acid Homeostasis Histone Modification Histone-serine Phosphorylation Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Cholesterol Metabolic Process Organelle Organization Sterol Metabolic Process Negative Regulation Of TOR Signaling Cholesterol Biosynthetic Process Translational Termination Positive Regulation Of Autophagy Neuron Recognition Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Synaptic Target Recognition Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Double-strand Break Repair Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Histone Phosphorylation Sterol Biosynthetic Process Protein Ubiquitination Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Anion Homeostasis Translational Elongation Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Process Regulation Of RNA Metabolic Process Cerebellum Structural Organization	Positive Regulation Of Protein Homooligomerization Positive Regulation Of Protein Oligomerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Release Of Cytochrome C From Mitochondria Synapse Organization Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Regulation Of Intracellular Signal Transduction Receptor Clustering Neuromuscular Junction Development Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Glycine Receptor Clustering Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Developmental Pigmentation Positive Regulation Of Cellular Component Biogenesis Apoptotic Signaling Pathway Protein Localization To Membrane Membrane Organization Positive Regulation Of Protein Linear Polyubiquitination Signaling Regulation Of Mitochondrion Organization Cellular Localization Positive Regulation Of Organelle Organization Cell Communication Vesicle Transport Along Actin Filament Establishment Of Synaptic Specificity At Neuromuscular Junction Endoplasmic Reticulum Localization Apoptotic Process Pigmentation Programmed Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process By Virus Odontogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Fibroblast Apoptotic Process Somite Specification Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Thymocyte Apoptotic Process Anoikis Locomotion Involved In Locomotory Behavior Histone H3-T11 Phosphorylation
Tagcloud ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?