CHPF and NPBWR2

		CHPF	NPBWR2
Description		chondroitin polymerizing factor	neuropeptides B and W receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Matrix Golgi Apparatus Cytosol Membrane Golgi Cisterna Membrane	Plasma Membrane Membrane Neuron Projection
	Molecular Function	Protein Binding Acetylgalactosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity	G Protein-coupled Receptor Activity G Protein-coupled Opioid Receptor Activity Protein Binding Neuropeptide Receptor Activity Neuropeptide Binding
	Biological Process	Chondroitin Sulfate Proteoglycan Biosynthetic Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway
Pathways		CS-GAG biosynthesis	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS			Body mass index ( 25673413) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Medication use (agents acting on the renin-angiotensin system) ( 31015401)
Interacting Genes		11 interacting genes: ARHGEF5 BTRC EXOSC10 EXOSC6 LCOR LINC00839 NKX3-1 PIN1 PRKN SKIL SMAD9	18 interacting genes: BOLL CYSRT1 KPRP KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP6-2 NOTCH2NLA NPB NPW PHAF1 PNMA1 PSMA3
Entrez ID		79586	2832
HPRD ID		10829	02841
Ensembl ID		ENSG00000123989	ENSG00000125522
Uniprot IDs		Q8IZ52	P48146
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Ligase Activator Activity Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Poly(A)-dependent SnoRNA 3'-end Processing Nuclear MRNA Surveillance Nucleolar Exosome (RNase Complex) Exosome (RNase Complex) Nuclear Exosome (RNase Complex) Sno(s)RNA Metabolic Process Beta-catenin Binding Ubiquitin-specific Protease Binding Regulation Of Dopamine Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Protein Localization Positive Regulation Of Establishment Of Protein Localization Histone Deacetylase Binding Protein K6-linked Ubiquitination Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Exocytosis Regulation Of Phosphorylation Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Nuclear Estrogen Receptor Binding Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Androgen Secretion Regulation Of Intrinsic Apoptotic Signaling Pathway MADS Box Domain Binding Negative Regulation Of Spontaneous Neurotransmitter Secretion Regulation Of Protein Targeting To Mitochondrion Cis-trans Isomerase Activity RNA Surveillance Nuclear RNA Surveillance Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Regulation Of Primary Metabolic Process Leukocyte Cell-cell Adhesion Integrin AlphaL-beta2 Complex Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Dorsal Aorta Development Positive Regulation Of Retrograde Transport, Endosome To Golgi SCF Ubiquitin Ligase Complex Negative Regulation Of Intralumenal Vesicle Formation Positive Regulation Of Protein Linear Polyubiquitination	Intermediate Filament Keratin Filament Epidermis Development Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Establishment Of Skin Barrier Tissue Development Structural Molecule Activity Skin Epidermis Development
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