NPBWR2 and PHAF1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		NPBWR2	PHAF1
Name		neuropeptides B and W receptor 2	phagophore assembly factor 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection	Phagophore Assembly Site Cytoplasm Trans-Golgi Network Dendrite Synaptic Vesicle Membrane
	Molecular Function	G Protein-coupled Receptor Activity G Protein-coupled Opioid Receptor Activity Protein Binding Neuropeptide Receptor Activity Neuropeptide Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway G Protein-coupled Opioid Receptor Signaling Pathway	Golgi To Plasma Membrane Protein Transport
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	None
GWAS		Body mass index ( 25673413 ) Cerebrospinal AB1-42 levels in normal cognition ( 29274321 ) Medication use (agents acting on the renin-angiotensin system) ( 31015401 )	No GWAS studies recorded
Novel Interactors		2 novel interactors: CHPF RRM2	3 novel interactors: CYB5B ESRP2 QSOX1
Interacting Genes		18 interacting genes: BOLL CYSRT1 KPRP KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 KRTAP6-2 NOTCH2NLA NPB NPW PHAF1 PNMA1 PSMA3	10 interacting genes: APP ATXN3 CBFA2T2 CCDC102B KIF17 MPPED1 NPBWR2 PRR5L TOLLIP TSHZ2
Entrez ID		2832	80262
HPRD ID		02841	17460
Ensembl ID		ENSG00000125522	ENSG00000125149
Uniprot IDs		P48146	Q9BSU1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Epidermis Development Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Establishment Of Skin Barrier Tissue Development Structural Molecule Activity Skin Epidermis Development	None