BUB3 and RPL37A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BUB3	RPL37A
Gene Name		BUB3 mitotic checkpoint protein	ribosomal protein L37a
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol	Nucleus Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Structural Constituent Of Ribosome Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Mitotic Spindle Assembly Checkpoint Attachment Of Spindle Microtubules To Kinetochore Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Division Meiotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Spindle Assembly Checkpoint	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Inactivation of APC/C via direct inhibition of the APC/C complex APC/C:Cdc20 mediated degradation of mitotic proteins Mitotic Anaphase Regulation of APC/C activators between G1/S and early anaphase Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components M Phase APC/C-mediated degradation of cell cycle proteins Cell Cycle, Mitotic Inactivation of APC/C via direct inhibition of the APC/C complex Mitotic Spindle Checkpoint Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components Resolution of Sister Chromatid Cohesion Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Regulation of mitotic cell cycle APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Cell Cycle Checkpoints Mitotic Metaphase and Anaphase	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: BUB1 BUB1B CPNE1 EXOC3 HDAC1 HDAC2 NKAP PARP1 PARP2 PSTPIP1 RPL37A SUGT1 THRA TOP1 UBA1 WBP4 ZNF207	7 interactors: APP BUB3 CTPS2 IFNGR2 LRIF1 MAGEA6 NKX3-1
Entrez ID		9184	6168
HPRD ID		04761	17997
Ensembl ID		ENSG00000154473
Uniprot IDs		O43684	P61513
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Fungiform Papilla Formation Negative Regulation Of Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Fungiform Papilla Morphogenesis Negative Regulation Of Cellular Protein Catabolic Process Circadian Regulation Of Gene Expression Positive Regulation Of Receptor Biosynthetic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Fungiform Papilla Development Eyelid Development In Camera-type Eye Negative Regulation Of Chromosome Organization Negative Regulation Of Cellular Metabolic Process Hair Follicle Placode Formation Tongue Morphogenesis Mitotic Nuclear Division Regulation Of Receptor Biosynthetic Process Negative Regulation Of Protein Catabolic Process Histone H4 Deacetylation Regulation Of Mitotic Nuclear Division Organelle Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein ADP-ribosylation Mitotic Cell Cycle Checkpoint Cell Division Histone H3 Deacetylation Circadian Rhythm Transcription Initiation From RNA Polymerase II Promoter Tongue Development Chromatin Remodeling Histone H3-K9 Modification Regulation Of Proteasomal Protein Catabolic Process Intracellular Receptor Signaling Pathway Regulation Of Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle	Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction 'de Novo' CTP Biosynthetic Process Positive Regulation Of Androgen Secretion Regulation Of Proteolysis Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding Collateral Sprouting Axon Midline Choice Point Recognition Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Axon Choice Point Recognition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Receptor Binding Regulation Of Cell Division Regulation Of Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Neuron Remodeling Positive Regulation Of Cell Cycle Dorsal Aorta Development Positive Regulation Of Proteolysis Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Attachment Of Spindle Microtubules To Kinetochore
Tagcloud ?		abrogates anaphase apc assembles attached bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently trip13 turned	3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc
Tagcloud (Difference) ?		abrogates anaphase apc assembles attached bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently trip13 turned	3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc
Tagcloud (Intersection) ?