ULBP3 and KLRK1

Number of citations of the paper that reports this interaction (PMID 11754823)
23

Data Source:
HPRD (in vitro)

		ULBP3	KLRK1
Gene Name		UL16 binding protein 3	killer cell lectin-like receptor subfamily K, member 1
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Anchored Component Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Peptide Antigen Binding Natural Killer Cell Lectin-like Receptor Binding	Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Viral Process Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	DAP12 signaling DAP12 interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Alopecia areata ( 20596022) Metabolite levels (HVA/5-HIAA ratio) ( 23319000)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		1 interactors: KLRK1	7 interactors: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3
Entrez ID		79465	22914
HPRD ID		16144	17240
Ensembl ID		ENSG00000131019	ENSG00000213809
Uniprot IDs		B4DN91 Q9BZM4	P26718
PDB IDs		1KCG	1HYR 1KCG 1MPU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Natural Killer Cell Activation T Cell Costimulation Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Innate Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Regulation Of Cell Activation Leukocyte Activation Regulation Of Cell Adhesion Positive Regulation Of Immune Response Cell Activation Innate Immune Response	Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Mediated Immunity Antigen Processing And Presentation Innate Immune Response Regulation Of Immune Response T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Immune System Process Defense Response Antigen Processing And Presentation Of Peptide Antigen T Cell Mediated Immunity Immune System Process Leukocyte Activation Viral Process Cell Activation Response To Stress Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Osteoclast Development Gamma-delta T Cell Activation Adaptive Immune Response Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Macrophage Activation Involved In Immune Response Lymphocyte Activation Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Response To Stimulus Macrophage Activation Regulation Of Defense Response To Virus By Host Mitotic Nuclear Envelope Disassembly
Tagcloud ?		antimyeloma ark constitutively degranulation engagement erk expressions hdac histocompatibility immunotherapeutic killer lysis mic mica myeloma nk nkg2d nkp30 nkp44 nkp46 pd98059 ul16 ulbp1 ulbp2 ulbp4 upregulate valproic vpa	15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus nkg2d rational regrowth ruxolitinib signature signatures systemically therapeutically topical
Tagcloud (Difference) ?		antimyeloma ark constitutively degranulation engagement erk expressions hdac histocompatibility immunotherapeutic killer lysis mic mica myeloma nk nkp30 nkp44 nkp46 pd98059 ul16 ulbp1 ulbp2 ulbp4 upregulate valproic vpa	15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus rational regrowth ruxolitinib signature signatures systemically therapeutically topical
Tagcloud (Intersection) ?		nkg2d