BRCC3 and SNAPC5

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		BRCC3	SNAPC5
Gene Name		BRCA1/BRCA2-containing complex, subunit 3	small nuclear RNA activating complex, polypeptide 5, 19kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nuclear Ubiquitin Ligase Complex Nucleus Nucleoplasm BRCA1-A Complex BRISC Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Enzyme Regulator Activity Polyubiquitin Binding Metal Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Double-strand Break Repair Proteolysis Response To X-ray Response To Ionizing Radiation G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Regulation Of Catalytic Activity Protein K63-linked Deubiquitination Histone H2A K63-linked Deubiquitination	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter Gene Expression
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BRCA1 FANCG SNAPC5 SUMO2 UBC UBE2D1 UIMC1	14 interactors: AMOT BATF BRCC3 CYTH4 DDIT3 JUN NDEL1 NMI NOL4 NUDT10 NUP62 SNAPC1 SNAPC4 SSSCA1
Entrez ID		79184	10302
HPRD ID		06465	16183
Ensembl ID		ENSG00000185515	ENSG00000174446
Uniprot IDs		P46736	O75971
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Checkpoint Cell Cycle Process Response To Abiotic Stimulus Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process DNA Damage Checkpoint Cell Cycle DNA Repair Protein Polyubiquitination Protein Modification By Small Protein Conjugation Cellular Response To Stress Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Protein Catabolic Process DNA-templated Transcription, Initiation G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Transcription, DNA-templated TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Protein Catabolic Process Regulation Of DNA Repair Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Response To DNA Damage Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Toll-like Receptor 3 Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity Positive Regulation Of Protein Metabolic Process Response To Radiation Negative Regulation Of Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Chromosome Organization Regulation Of Cell Cycle Process	Regulation Of Small GTPase Mediated Signal Transduction Transcription, DNA-templated Regulation Of Catalytic Activity RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear Envelope Disassembly Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase III Promoter Regulation Of Ras Protein Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cell Cycle Positive Regulation Of Neuron Apoptotic Process Nitrogen Compound Metabolic Process Nuclear Envelope Organization Negative Regulation Of Determination Of Dorsal Identity Cellular Response To Potassium Ion Starvation Regulation Of GTPase Activity RNA Metabolic Process Positive Regulation Of Neuron Death Transcription From RNA Polymerase II Promoter Gene Expression Leading Edge Cell Differentiation ADP Catabolic Process Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Regulation Of Transcription Involved In Anterior/posterior Axis Specification Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Intracellular Signal Transduction Histone H2A K63-linked Deubiquitination IDP Catabolic Process Establishment Of Cell Polarity Positive Regulation Of Hydrolase Activity Myeloid Leukocyte Differentiation Nucleus Organization Regulation Of Signal Transduction T-helper 2 Cell Differentiation Intracellular Signal Transduction Regulation Of Cell Size Blood Vessel Development T-helper 17 Cell Lineage Commitment SnRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Vasculature Development
Tagcloud ?		break brip1 carcinogen carcinogenic ccna2 ccnb1 ccng1 chek1 cor cyce1 deregulated dsb genotoxicity gpt kidneys medulla ochratoxin om ota outer phlda3 possessed rad18 rodents s3 segment tubules tumorigenicity wee1
Tagcloud (Difference) ?		break brip1 carcinogen carcinogenic ccna2 ccnb1 ccng1 chek1 cor cyce1 deregulated dsb genotoxicity gpt kidneys medulla ochratoxin om ota outer phlda3 possessed rad18 rodents s3 segment tubules tumorigenicity wee1
Tagcloud (Intersection) ?