GNPTAB and AEN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GNPTAB	AEN
Gene Name		N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	apoptosis enhancing nuclease
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Golgi Apparatus Integral Component Of Membrane	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Calcium Ion Binding Transcription Factor Binding	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Lysosome Organization Protein Secretion Cell Differentiation Carbohydrate Phosphorylation	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: AEN APP DISC1 FAM90A1 MAPK1 PSMA1 STAMBPL1 ZNF250	33 interactors: AAMP AES EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SSX2IP TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		79158	64782
HPRD ID		11350	08573
Ensembl ID		ENSG00000111670	ENSG00000181026
Uniprot IDs		Q3T906	Q8WTP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Apoptotic Process Programmed Cell Death Cell Death Death Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Synapse Structure Or Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction By P53 Class Mediator MAPK Import Into Nucleus Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Ubiquitination Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Regulation Of Golgi Inheritance Regulation Of Cellular Protein Metabolic Process Platelet Activation Caveolin-mediated Endocytosis Collateral Sprouting Axon Midline Choice Point Recognition Cytosine Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Protein Ubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Regulation Of Cell Cycle Phase Transition Regulation Of Protein Metabolic Process Regulation Of Golgi Organization Neuron Remodeling Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Regulation Of Translation Positive Regulation Of Cell Cycle Response To Abiotic Stimulus Cellular Calcium Ion Homeostasis Regulation Of Wnt Signaling Pathway Calcium Ion Homeostasis Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Cellular Metabolic Process	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process MRNA Processing Positive Regulation Of Neutrophil Differentiation Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Androgen Secretion Regulation Of Viral Transcription Cellular Metabolic Process RNA Processing Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Estrogen Receptor Binding Regulation Of Wnt Signaling Pathway Response To Interleukin-1 Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding Negative Regulation Of Nucleic Acid-templated Transcription Histone MRNA 3'-end Processing RNA Splicing Biosynthetic Process Intraciliary Transport Involved In Cilium Morphogenesis
Tagcloud ?		bioinformatic desaturation diabesity discriminant dock1 elutriated ether fam126a goes granulocytes klf4 lipidome lipidomic monocyte mufa nfy pdk4 pe peroxisomal phagocytic plasmalogen plasmalogens pls pufa rhm rnf96 silico squares transcriptomic	abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Difference) ?		bioinformatic desaturation diabesity discriminant dock1 elutriated ether fam126a goes granulocytes klf4 lipidome lipidomic monocyte mufa nfy pdk4 pe peroxisomal phagocytic plasmalogen plasmalogens pls pufa rhm rnf96 silico squares transcriptomic	abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Intersection) ?