BBLN and INPP1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		BBLN	INPP1
Description		bublin coiled coil protein	inositol polyphosphate-1-phosphatase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Kinetochore Microtubule Cytoskeleton Intermediate Filament Cell Junction Anchoring Junction Subapical Part Of Cell	Cytosol
	Molecular Function	Protein Binding Molecular Adaptor Activity	Inositol-1,4-bisphosphate 1-phosphatase Activity Protein Binding Hydrolase Activity Metal Ion Binding Inositol-1,3,4-trisphosphate 1-phosphatase Activity
	Biological Process	Apoptotic Process Gene Expression Osteoclast Differentiation Intermediate Filament Bundle Assembly Bone Resorption Bone Development Multinuclear Osteoclast Differentiation Apoptotic Signaling Pathway	Phosphate-containing Compound Metabolic Process Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process
Pathways			Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS			Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Lung cancer (SNP x SNP interaction) ( 24325914) Machado-Joseph disease (age at onset) ( 32205469)
Interacting Genes		7 interacting genes: ATP6V1E2 CEP290 FGD4 IKBIP INPP1 KRT20 THAP11	11 interacting genes: BBLN BRCA1 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1
Entrez ID		79095	3628
HPRD ID		12946	00923
Ensembl ID		ENSG00000171159	ENSG00000151689
Uniprot IDs		Q9BUW7	P49441 Q6IBG4
PDB IDs
Enriched GO Terms of Interacting Partners?			DNA Strand Resection Involved In Replication Fork Processing Histone H2AK127 Ubiquitin Ligase Activity DNA Metabolic Process Histone H2AK129 Ubiquitin Ligase Activity Homologous Recombination Cellular Response To Tumor Necrosis Factor Chromosome BRCA1-BARD1 Complex DNA Recombination Okazaki Fragment Processing Involved In Mitotic DNA Replication DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Replication, Okazaki Fragment Processing DNA Ligase Activity Deoxyribonuclease Inhibitor Activity Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Negative Regulation Of Astrocyte Activation Circadian Temperature Homeostasis Positive Regulation Of Bile Acid Biosynthetic Process G2/MI Transition Of Meiotic Cell Cycle Kinetochore Adaptor Activity Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Adenosine Receptor Signaling Pathway A2A Adenosine Receptor Binding Subapical Part Of Cell Multinuclear Osteoclast Differentiation BRCA1-B Complex Cell Division Meiotic Cell Cycle Phase Transition Ndc80 Complex Spindle Assembly Involved In Female Meiosis I Type 5 Metabotropic Glutamate Receptor Binding Response To Tumor Necrosis Factor
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