REEP5 and CPOX

Data Source: HiPPIP (Novel)

		REEP5	CPOX
Name		receptor accessory protein 5	coproporphyrinogen oxidase
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane
	Molecular Function	Protein Binding	Coproporphyrinogen Oxidase Activity Structural Constituent Of Eye Lens Oxidoreductase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Endoplasmic Reticulum Membrane Organization	Porphyrin-containing Compound Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Heme A Biosynthetic Process Heme B Biosynthetic Process Response To Iron Ion Response To Lead Ion Response To Insecticide Response To Arsenic-containing Substance Heme O Biosynthetic Process Response To Methylmercury
Pathways		None	Heme biosynthesis
Diseases		None	Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS		Attention deficit hyperactivity disorder ( 18839057 ) Daytime nap ( 33568662 ) Reaction time ( 29844566 )	Refractive error ( 32231278 )
Novel Interactors		9 novel interactors: CD14 CPOX EDC3 GPX3 HBEGF LGR5 PDK4 PDLIM3 TENT4A	2 novel interactors: ATXN7 REEP5
Interacting Genes		13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1	1 interacting genes: UBE2G2
Entrez ID		7905	1371
HPRD ID		15918	00417
Ensembl ID		ENSG00000129625	ENSG00000080819
Uniprot IDs		Q00765	P36551
PDB IDs		Not available	2AEX