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CPOX

Name coproporphyrinogen oxidase
Structure PDB 2AEX
Novel Interactors 2 novel interactors: ATXN7 REEP5
Interactors 1 interactors: UBE2G2
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Intermembrane Space
  • Cytosol
  • Membrane
Molecular Function
  • Coproporphyrinogen Oxidase Activity
  • Structural Constituent Of Eye Lens
  • Oxidoreductase Activity
  • Identical Protein Binding
  • Protein Homodimerization Activity
Biological Process
  • Porphyrin-containing Compound Biosynthetic Process
  • Protoporphyrinogen IX Biosynthetic Process
  • Heme Biosynthetic Process
  • Heme A Biosynthetic Process
  • Heme B Biosynthetic Process
  • Response To Iron Ion
  • Response To Lead Ion
  • Response To Insecticide
  • Response To Arsenic-containing Substance
  • Heme O Biosynthetic Process
  • Response To Methylmercury
Pathways
  • Heme biosynthesis
Diseases
  • Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS
  • Refractive error ( 32231278 )
Entrez ID 1371
HPRD ID 00417
Ensembl ID ENSG00000080819
Uniprot IDs P36551
PDB IDs 2AEX

© Madhavi K. Ganapathiraju 2012-2026