CPOX and REEP5

Data Source: HiPPIP (Novel)

		CPOX	REEP5
Name		coproporphyrinogen oxidase	receptor accessory protein 5
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Coproporphyrinogen Oxidase Activity Structural Constituent Of Eye Lens Oxidoreductase Activity Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Porphyrin-containing Compound Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Heme A Biosynthetic Process Heme B Biosynthetic Process Response To Iron Ion Response To Lead Ion Response To Insecticide Response To Arsenic-containing Substance Heme O Biosynthetic Process Response To Methylmercury	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Endoplasmic Reticulum Membrane Organization
Pathways		Heme biosynthesis	None
Diseases		Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)	None
GWAS		Refractive error ( 32231278 )	Attention deficit hyperactivity disorder ( 18839057 ) Daytime nap ( 33568662 ) Reaction time ( 29844566 )
Novel Interactors		2 novel interactors: ATXN7 REEP5	9 novel interactors: CD14 CPOX EDC3 GPX3 HBEGF LGR5 PDK4 PDLIM3 TENT4A
Interacting Genes		1 interacting genes: UBE2G2	13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1
Entrez ID		1371	7905
HPRD ID		00417	15918
Ensembl ID		ENSG00000080819	ENSG00000129625
Uniprot IDs		P36551	Q00765
PDB IDs		2AEX	Not available