GAD2 and CMTM5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GAD2	CMTM5
Gene Name		glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	CKLF-like MARVEL transmembrane domain containing 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Cell Junction Axon Synaptic Vesicle Membrane Anchored Component Of Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane	Extracellular Space Integral Component Of Membrane
	Molecular Function	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein Heterodimerization Activity	Cytokine Activity
	Biological Process	Glutamate Decarboxylation To Succinate Synaptic Transmission Neurotransmitter Secretion Neurotransmitter Biosynthetic Process Response To Drug	Chemotaxis Negative Regulation Of Myoblast Differentiation
Pathways		Neurotransmitter Release Cycle GABA synthesis GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AGTRAP ARL6IP1 CMTM5 F10 GAD1 MAL2 PRKACA PRKCE TMEM159	46 interactors: AACS ACSF2 ALDH18A1 APOA1 ARMC9 C12orf10 CPLX1 CYP1A1 DDA1 FAM114A1 FARS2 GAD1 GAD2 GLTP GOLGA2P10 GTF3C1 KIAA0368 LMO2 MCEE MTERF3 NDRG4 PITPNC1 PLIN3 PPIF PPP2R3C PTPN9 RBFA RMDN2 RNF185 RSRC2 SDCBP SH3GLB1 SHMT2 SNX1 SPATA8 SPG21 SSX3 SUCLA2 SYNE4 TIMM44 TPD52L3 TTPA TUBB TUFM VARS2 ZNF391
Entrez ID		2572	116173
HPRD ID		11817	06986
Ensembl ID		ENSG00000136750	ENSG00000166091
Uniprot IDs		Q05329 Q5VZ30	C9JAI6 Q96DZ9
PDB IDs		1ES0 2OKK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Migration Activation Of Phospholipase C Activity Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Positive Regulation Of Phospholipase C Activity Blood Coagulation Hemostasis Positive Regulation Of Phospholipase Activity Positive Regulation Of Epithelial Cell Migration Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Cellular Glucuronidation Regulation Of Body Fluid Levels Regulation Of Cell Migration Peptidyl-serine Phosphorylation Wound Healing Glutamate Decarboxylation To Succinate TRAM-dependent Toll-like Receptor 4 Signaling Pathway Protein-pyridoxal-5-phosphate Linkage Histone H3-T6 Phosphorylation Regulation Of Cell Motility Regulation Of Wound Healing Regulation Of Locomotion Regulation Of Ion Transmembrane Transporter Activity Regulation Of Epithelial Cell Migration Regulation Of Transmembrane Transporter Activity Regulation Of Cellular Component Movement Response To Wounding Regulation Of Ion Homeostasis Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Gamma-aminobutyric Acid Biosynthetic Process Cytosolic Calcium Ion Homeostasis Positive Regulation Of Intracellular Signal Transduction Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Platelet Activation Blood Coagulation, Extrinsic Pathway Regulation Of Insulin Secretion Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Peptide Hormone Secretion Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Glutamate Catabolic Process Peptidyl-serine Autophosphorylation	Carboxylic Acid Metabolic Process Succinate Metabolic Process Organic Acid Metabolic Process Glutamate Decarboxylation To Succinate Glutamate Metabolic Process Dicarboxylic Acid Metabolic Process Small Molecule Metabolic Process Glutamate Catabolic Process Cellular Amino Acid Metabolic Process Dicarboxylic Acid Catabolic Process Neurotransmitter Biosynthetic Process Response To Nutrient Neurotransmitter Secretion Response To Arsenic-containing Substance Alpha-amino Acid Metabolic Process Neurotransmitter Metabolic Process Cellular Metabolic Process Cellular Amino Acid Biosynthetic Process Response To Drug Regulation Of Neurotransmitter Levels Fatty Acid Metabolic Process Monocarboxylic Acid Metabolic Process Ornithine Biosynthetic Process Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Succinyl-CoA Pathway Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Establishment Of Blood-brain Barrier L-methylmalonyl-CoA Metabolic Process Dibenzo-p-dioxin Catabolic Process Cofactor Metabolic Process Neurotransmitter Transport Establishment Of Localization In Cell Porphyrin-containing Compound Metabolic Process Valyl-tRNA Aminoacylation Negative Regulation Of Oxidative Phosphorylation Uncoupler Activity Protein-pyridoxal-5-phosphate Linkage Uroporphyrinogen III Biosynthetic Process Negative Regulation Of Interleukin-1 Beta Secretion Regulation Of Establishment Of Blood-brain Barrier
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	author bio chance chip chosen cyclin d1 discover egfr epithelium her2 ihc insure makes manners next partner pc3 performance plasmid plays prostate regulated relationship stream traditional transduction transfection whether
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx	author bio chance chip chosen cyclin d1 discover egfr epithelium her2 ihc insure makes manners next partner pc3 performance plasmid plays prostate regulated relationship stream traditional transduction transfection whether
Tagcloud (Intersection) ?