RNF113A and SNRNP200

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		RNF113A	SNRNP200
Gene Name		ring finger protein 113A	small nuclear ribonucleoprotein 200kDa (U5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Zinc Ion Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding
	Biological Process		Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CCAR1 ILF3 RBM39 SNRNP200 TERF2 TRIM8 UBE2U	19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG
Entrez ID		7737	23020
HPRD ID		06760	03391
Ensembl ID		ENSG00000125352	ENSG00000144028
Uniprot IDs		O15541	O75643
PDB IDs			2Q0Z 4F91 4F92 4F93 4KIT
Enriched GO Terms of Interacting Partners?		RNA Splicing Negative Regulation Of Viral Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cis Assembly Of Pre-catalytic Spliceosome Regulation Of Viral Process Telomeric Loop Formation Age-dependent Telomere Shortening Nitrogen Compound Metabolic Process Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Replicative Cell Aging Cellular Metabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Entry Into Host Cell MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Biosynthetic Process Regulation Of Telomere Maintenance Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Entry Into Host Cell Negative Regulation Of Viral Transcription RNA-dependent DNA Replication Regulation Of Viral Release From Host Cell RNA Metabolic Process Protein Localization To Chromosome Cellular Senescence Telomere Maintenance Via Telomere Lengthening Histone Ubiquitination Response To Stress Gene Expression Protein Ubiquitination Chromatin Modification Negative Regulation Of Viral Genome Replication Cellular Macromolecule Biosynthetic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication
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