RNF113A and RBM39

Number of citations of the paper that reports this interaction (PubMedID 35819319)
55

Data Source:
BioGRID (biochemical, two hybrid, two hybrid)

		RNF113A	RBM39
Description		ring finger protein 113A	RNA binding motif protein 39
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding Protein Binding RS Domain Binding U1 SnRNP Binding
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair MRNA Processing DNA Damage Response RNA Splicing Protein Ubiquitination SnoRNA Splicing Negative Regulation Of Chemokine-mediated Signaling Pathway	RNA Processing MRNA Processing RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		10 interacting genes: CCAR1 CXCR4 PPP4R3A RBM39 SMYD3 SNRNP200 TERF2 TRIM8 UBE2D3 UBE2U	56 interacting genes: AK8 APP ARL6IP4 ASH2L BANP CEBPA CHERP CLK2 CSNK2A1 DARS1-AS1 DCAF15 DDX39B DVL3 ESR1 ESR2 FAM200A GOLGA2 HOMEZ INO80B JUN KHDC4 KMT2A KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 OGT PGR PHC2 POU6F2 PRPF38A PRPF40A RBBP5 RBM23 RBM25 REL RNF113A RP9P SAP30BP SDCBP SF3B4 SP100 SREK1 SREK1IP1 SRRM4 THAP1 TOE1 TTC14 U2AF2 USP7 WDR5 ZBTB22 ZCCHC10
Entrez ID		7737	9584
HPRD ID		06760	09201
Ensembl ID		ENSG00000125352	ENSG00000131051
Uniprot IDs		O15541	A0A384NQ03 B4DRA0 Q14498
PDB IDs		5Z56 5Z58 6FF4 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U	2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6PAI 6Q0R 6Q0V 6Q0W 6SJ7 6UD7 6UE5 7Q33
Enriched GO Terms of Interacting Partners?		Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination DNA Damage Response Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Telomere Single Strand Break Repair Telomeric Loop Formation Negative Regulation Of DNA Recombination At Telomere Post-translational Protein Modification Protein Polyubiquitination Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin Conjugating Enzyme Activity C-X-C Motif Chemokine 12 Receptor Activity Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) Cis Assembly Of Pre-catalytic Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of T-circle Formation Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Nucleoplasm Negative Regulation Of Mitotic Recombination Histone H3K36 Dimethyltransferase Activity Telomerase Activity Protection From Non-homologous End Joining At Telomere Response To Stress Regulation Of Mitotic Recombination Shelterin Complex Nucleic Acid Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process CXCL12-activated CXCR4 Signaling Pathway Myosin Light Chain Binding C-X-C Chemokine Receptor CXCR4 Signaling Pathway RS Domain Binding U1 SnRNP Binding Protein Phosphatase 4 Complex Histone H4 Methyltransferase Activity HULC Complex Negative Regulation Of Telomere Capping Regulation Of Metabolic Process Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway C-X-C Chemokine Receptor Activity RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Histone H3K4 Trimethyltransferase Activity	Nucleoplasm RNA Splicing MRNA Processing MRNA Metabolic Process MLL1/2 Complex Regulation Of RNA Metabolic Process Histone Methyltransferase Complex Nucleus RNA Metabolic Process MLL3/4 Complex RNA Processing Nucleic Acid Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression, Epigenetic Nuclear Speck Nucleobase-containing Compound Metabolic Process Nucleic Acid Binding Spliceosomal Complex MLL1 Complex Regulation Of Transcription By RNA Polymerase II Estrogen Response Element Binding Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Set1C/COMPASS Complex Negative Regulation Of Biosynthetic Process Rhythmic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Initiation-coupled Chromatin Remodeling Regulation Of Gluconeogenesis Negative Regulation Of RNA Metabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Nuclear Steroid Receptor Activity MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nuclear Estrogen Receptor Activity RNA Splicing, Via Transesterification Reactions Regulation Of Metabolic Process RNA Binding Negative Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process
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