HSD17B7 and DTYMK

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HSD17B7	DTYMK
Gene Name		hydroxysteroid (17-beta) dehydrogenase 7	deoxythymidylate kinase (thymidylate kinase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Nucleus Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Cytosol
	Molecular Function	3-keto Sterol Reductase Activity Estradiol 17-beta-dehydrogenase Activity Prolactin Receptor Binding	Thymidylate Kinase Activity ATP Binding Uridylate Kinase Activity Nucleoside Phosphate Kinase Activity
	Biological Process	Cholesterol Biosynthetic Process Estrogen Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process	DUDP Biosynthetic Process DTDP Biosynthetic Process DTTP Biosynthetic Process Cell Cycle Cell Proliferation Nucleobase-containing Small Molecule Interconversion Response To Estrogen Small Molecule Metabolic Process Myoblast Differentiation Response To Cadmium Ion Nucleotide Phosphorylation Nucleoside Monophosphate Phosphorylation Nucleobase-containing Small Molecule Metabolic Process Cellular Response To Growth Factor Stimulus
Pathways		Cholesterol biosynthesis Metabolism of lipids and lipoproteins	Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs		NADH	Thymidine-5\'-Phosphate 2\',3\'-Dideoxythymidine-5\'-Monophosphate Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester P1-(5\'-Adenosyl)P5-(5\'-Thymidyl)Pentaphosphate Adenosine-5\'-Diphosphate 3\'-Azido-3\'-Deoxythymidine-5\'-Monophosphate P1-(5\'-Adenosyl)P5-(5\'-(3\'azido-3\'-Deoxythymidyl))Pentaphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		6 interactors: AGPAT6 BRSK1 CA1 DTYMK GORAB VKORC1	1 interactors: HSD17B7
Entrez ID		51478	1841
HPRD ID		05996	01773
Ensembl ID		ENSG00000132196	ENSG00000168393
Uniprot IDs		P56937	B7ZW70 P23919 Q53F55 Q6FGU2
PDB IDs			1E2D 1E2E 1E2F 1E2G 1E2Q 1E98 1E99 1E9A 1E9B 1E9C 1E9D 1E9E 1E9F 1NMX 1NMY 1NMZ 1NN0 1NN1 1NN3 1NN5 2XX3
Enriched GO Terms of Interacting Partners?		Nucleoside Monophosphate Phosphorylation DTDP Biosynthetic Process Small Molecule Metabolic Process DUDP Biosynthetic Process Glandular Epithelial Cell Maturation Vitamin K Metabolic Process DTTP Biosynthetic Process Cofactor Metabolic Process Deoxyribonucleoside Diphosphate Metabolic Process Nucleoside Diphosphate Biosynthetic Process CDP-diacylglycerol Biosynthetic Process CDP-diacylglycerol Metabolic Process Peptidyl-glutamic Acid Carboxylation Deoxyribonucleotide Biosynthetic Process Diacylglycerol Metabolic Process Nucleobase-containing Small Molecule Interconversion Epithelial Cell Maturation Phosphatidylcholine Biosynthetic Process Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Deoxyribonucleoside Triphosphate Metabolic Process Regulation Of Body Fluid Levels Glandular Epithelial Cell Development Bicarbonate Transport Secretion Centrosome Duplication G2 DNA Damage Checkpoint One-carbon Metabolic Process Anatomical Structure Development Quinone Metabolic Process Drug Metabolic Process Triglyceride Biosynthetic Process Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Myoblast Differentiation Deoxyribonucleotide Metabolic Process Phosphatidylcholine Metabolic Process Pyrimidine Nucleotide Biosynthetic Process Developmental Process Centrosome Cycle Lactation Nucleotide Phosphorylation Response To Cadmium Ion Nucleoside Diphosphate Metabolic Process Acyl-CoA Metabolic Process Cellular Metabolic Process Phosphate-containing Compound Metabolic Process Pyrimidine Nucleotide Metabolic Process Cellular Ketone Metabolic Process Organophosphate Metabolic Process	Estrogen Biosynthetic Process Estrogen Metabolic Process Cholesterol Biosynthetic Process Sterol Biosynthetic Process Hormone Biosynthetic Process Cholesterol Metabolic Process Steroid Biosynthetic Process Sterol Metabolic Process Hormone Metabolic Process Steroid Metabolic Process Regulation Of Hormone Levels Alcohol Metabolic Process Lipid Biosynthetic Process
Tagcloud ?		1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase sult1a1 sult2b1 ugt2b7
Tagcloud (Difference) ?		1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase sult1a1 sult2b1 ugt2b7
Tagcloud (Intersection) ?