XRCC2 and NKIRAS1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		XRCC2	NKIRAS1
Gene Name		X-ray repair complementing defective repair in Chinese hamster cells 2	NFKB inhibitor interacting Ras-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex	Cellular_component Cytoplasm Membrane
	Molecular Function	Four-way Junction DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity	GTPase Activity GTP Binding
	Biological Process	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination In Utero Embryonic Development Somitogenesis DNA Repair Meiotic Nuclear Division Response To X-ray Response To Gamma Radiation Multicellular Organism Growth Strand Invasion Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Centrosome Organization Regulation Of Fibroblast Apoptotic Process	I-kappaB Kinase/NF-kappaB Signaling Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS		Palmitic acid (16:0) plasma levels ( 23362303)
Protein-Protein Interactions		4 interactors: MEOX2 NKIRAS1 RAD51D WFDC1	8 interactors: ACVR1 APP BMPR1B NFKBIA NFKBIB SMURF2 TGFBR1 XRCC2
Entrez ID		7516	28512
HPRD ID		02656	06841
Ensembl ID		ENSG00000196584	ENSG00000197885
Uniprot IDs		O43543	Q9NYS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Strand Invasion	Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway BMP Signaling Pathway Regulation Of Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Reproduction Pathway-restricted SMAD Protein Phosphorylation Response To Stress Pattern Specification Process Transforming Growth Factor Beta Receptor Signaling Pathway Pharyngeal System Development Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Growth Factor Response To Transforming Growth Factor Beta Defense Response Regulation Of Extrinsic Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Cellular Response To Stimulus Regulation Of Apoptotic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Death Regulation Of RNA Metabolic Process Regulation Of Signal Transduction Regulation Of Binding Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Sexual Reproduction Signal Transduction By Phosphorylation Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Response To Lipid Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Gene Expression Peptidyl-threonine Phosphorylation Regulation Of Signaling Regulation Of Nitrogen Compound Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Apoptotic Process Cellular Response To Organic Substance Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Programmed Cell Death Toll-like Receptor 10 Signaling Pathway Regulation Of Pathway-restricted SMAD Protein Phosphorylation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Signal Transduction Toll-like Receptor 2 Signaling Pathway
Tagcloud ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc3	17and 193a 34b alterations besides beta2 coding collection comprehensive consequently correlations cpg exact fisher histologically hundreds indirect inverse islands marginally methylation mir mirna mirnas spearman statistics target thousand turn
Tagcloud (Difference) ?		additive allele applying became bonferroni correction d312n damaged dominant ercc2 ethnical exoi gg insignificant polymorphism polymorphisms r399q recessive remaining repair rs1799793 rs25487 russian russians snps tt xrcc1 xrcc3	17and 193a 34b alterations besides beta2 coding collection comprehensive consequently correlations cpg exact fisher histologically hundreds indirect inverse islands marginally methylation mir mirna mirnas spearman statistics target thousand turn
Tagcloud (Intersection) ?