VIL1 and TEX11

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VIL1	TEX11
Description		villin 1	testis expressed 11
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytoskeleton Plasma Membrane Microvillus Brush Border Actin Cytoskeleton Lamellipodium Filopodium Actin Filament Bundle Filopodium Tip Cell Projection Extracellular Exosome	Condensed Nuclear Chromosome Synaptonemal Complex Central Element Chromosome
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lysophosphatidic Acid Binding Identical Protein Binding Protein Homodimerization Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Actin Filament Binding	Protein Binding
	Biological Process	Intestinal D-glucose Absorption Apoptotic Process Cytoskeleton Organization Actin Filament Organization Epidermal Growth Factor Receptor Signaling Pathway Actin Polymerization Or Depolymerization Regulation Of Cell Shape Response To Bacterium Positive Regulation Of Epithelial Cell Migration Actin Filament Polymerization Actin Filament Depolymerization Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Depolymerization Epithelial Cell Differentiation Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Microvillus Length Cellular Response To Hepatocyte Growth Factor Stimulus Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Cellular Component Biogenesis Actin Filament Severing Barbed-end Actin Filament Capping Regulation Of Actin Nucleation Actin Filament Capping Cytoplasmic Actin-based Contraction Involved In Cell Motility Regulation Of Wound Healing Protein-containing Complex Assembly Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Lamellipodium Organization Terminal Web Assembly Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Lamellipodium Morphogenesis Positive Regulation Of Lamellipodium Morphogenesis	Resolution Of Meiotic Recombination Intermediates Meiotic Gene Conversion Apoptotic Process Male Meiosis Chromosome Segregation Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiotic Nuclear Division Male Gonad Development Fertilization Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Chiasma Assembly Negative Regulation Of Developmental Process Meiotic Cell Cycle Negative Regulation Of Reproductive Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Estimated glomerular filtration rate ( 31152163) Height ( 31562340) Male-pattern baldness ( 28196072) Mean corpuscular hemoglobin ( 32888494) Red blood cell count ( 27863252) Waist-hip index ( 34021172)	Mean corpuscular volume ( 29403010) Waist circumference ( 28552196)
Interacting Genes		7 interacting genes: ACTA1 ACTG1 JAK3 PLCG1 RNF10 SRC TEX11	91 interacting genes: ATXN3 BCL2L2 BEX1 BORCS8 BORCS8-MEF2B BRMS1L CATSPERT CBY2 CCDC198 CCND2 CCND3 CD74 CDKN1A CDKN2D CENPP CEP55 CEP85L CFAP53 CLK1 CNOT7 COL20A1 CXCL14 DMTN DUSP21 DUSP6 EFHC1 EXOSC1 EXOSC5 FAAP20 FAM156A FAM161B FAM217A FBF1 GATAD2B GPSM3 GRXCR1 HOXB5 HYI ING3 KANK2 KCTD10 KIAA0408 KIAA1217 KRT6B LIN37 LRCH2 LRRC36 LSM2 MAD1L1 MAPK9 MAPKBP1 MORF4L1 MRFAP1 MRFAP1L1 MTA1 MYEF2 NECAB2 NEFL NRIP1 PEX39 PIAS1 POM121 PPP1R18 PRPSAP2 PTPDC1 QKI REXO1L6P RIBC1 RIBC2 SCAF8 SEPTIN1 SH3GLB2 SHOC1 SNW1 SNX32 SNX6 SNX7 SOX5 SPMIP5 STMN2 SUPT5H TBC1D22B TCHP TIPIN TOPBP1 TSC22D4 TSG101 USP15 UTP14C VIL1 ZNF414
Entrez ID		7429	56159
HPRD ID		01898	02256
Ensembl ID		ENSG00000127831	ENSG00000120498
Uniprot IDs		P09327 Q53F91	Q8IYF3
PDB IDs		1UNC 3FG7
Enriched GO Terms of Interacting Partners?		Actin Filament Negative Regulation Of Immune Response Negative Regulation Of Inflammatory Response To Antigenic Stimulus Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Positive Regulation Of Epithelial Cell Migration Fc Receptor Signaling Pathway Regulation Of Cell-substrate Junction Organization Basal Body Patch Regulation Of Focal Adhesion Assembly ERBB Signaling Pathway Regulation Of Epithelial Cell Migration Epidermal Growth Factor Receptor Signaling Pathway Meiotic Gene Conversion Structural Constituent Of Cytoskeleton ATP Binding Blood Microparticle Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell Migration Response To Peptide Positive Regulation Of Cell Motility Response To Cytokine Actomyosin Structure Organization Multicellular Organismal-level Homeostasis Negative Regulation Of Dendritic Cell Cytokine Production Response To Interleukin-9 Negative Regulation Of Immune System Process Response To Interleukin-2 Response To Interleukin-15 Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Developmental Process Ruffle Membrane Calcium-dependent Phospholipase C Activity Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Gene Conversion Male Meiosis Chromosome Segregation Positive Regulation Of Locomotion Regulation Of Apoptotic Process Regulation Of Transepithelial Transport Negative Regulation Of T-helper 1 Cell Differentiation Regulation Of Programmed Cell Death Cellular Response To Progesterone Stimulus Enzyme-linked Receptor Protein Signaling Pathway Nucleotide Binding Lamellipodium Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Protein Localization To Bicellular Tight Junction Structural Constituent Of Postsynaptic Actin Cytoskeleton	Axonemal A Tubule Inner Sheath Protein Binding Cytoskeleton Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility RNA Exonuclease Activity Cilium Movement Involved In Cell Motility Cyclin D2-CDK4 Complex Negative Regulation Of Peptidyl-tyrosine Phosphorylation Motile Cilium Spindle Pole
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