UTY and PRDX2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UTY	PRDX2
Gene Name		ubiquitously transcribed tetratricopeptide repeat containing, Y-linked	peroxiredoxin 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function	Metal Ion Binding Dioxygenase Activity Histone Demethylase Activity (H3-K27 Specific)	Thioredoxin Peroxidase Activity Antioxidant Activity
	Biological Process	Regulation Of Gene Expression Oxidation-reduction Process Histone H3-K27 Demethylation	Response To Reactive Oxygen Species Response To Oxidative Stress Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Oxidation-reduction Process
Pathways			Detoxification of Reactive Oxygen Species
Drugs			3-Sulfinoalanine N-Carbamoyl-Alanine
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PRDX2 TLE1 TLE2	23 interactors: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 UTY YWHAZ
Entrez ID		7404	7001
HPRD ID		02451	02763
Ensembl ID		ENSG00000183878	ENSG00000167815
Uniprot IDs		E1NZ93 E1U198 E1U1M3 E1U1M9 F4MH27 F4MH29 F4MH30 F4MH31 F4MH32 F4MH35 F4MH36 F4MH40 F4MH46 F4MH47 F4MH50 F4MH51 F4MH58 F4MH60 F4MH62 F4MH91 F4MH92 F5GWV3 F5H3N7 O14607	A6NIW5 B4DF70 P32119
PDB IDs		3ZLI 3ZPO	1QMV
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Negative Regulation Of Anoikis Hydrogen Peroxide Catabolic Process Regulation Of Anoikis Removal Of Superoxide Radicals Cellular Response To Superoxide Response To Superoxide Response To Oxygen Radical Hydrogen Peroxide Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Superoxide Metabolic Process Organ Morphogenesis Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Apoptotic Process Regulation Of Cell Death Cellular Response To Reactive Oxygen Species Reactive Oxygen Species Metabolic Process	Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Signal Transduction Regulation Of Signaling Establishment Of Localization In Cell Secretion By Cell Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Cell Death Secretion Intracellular Signal Transduction Cellular Localization Cellular Component Assembly Vesicle-mediated Transport Regulation Of Cellular Component Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Response To Oxidative Stress Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Synapse Assembly Protein Metabolic Process Positive Regulation Of Signal Transduction Membrane Organization Immune Response Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Regulation Of Catalytic Activity Homeostatic Process Anatomical Structure Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Receptor Activity Positive Regulation Of Programmed Cell Death Apoptotic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Programmed Cell Death Developmental Process Cell Death Anion Transport Regulation Of Proteolysis Death Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Phosphorylation Regulation Of Cell Death Mitochondrial Transport Postsynaptic Membrane Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?		2gamma chromosome dffry dmd encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously xp21 zfy1 zfy2	2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Difference) ?		2gamma chromosome dffry dmd encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously xp21 zfy1 zfy2	2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Intersection) ?