CLRN1 and TMIE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLRN1	TMIE
Description		clarin 1	transmembrane inner ear
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Microvillus Microtubule Cytoskeleton Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell Actin-based Cell Projection	Membrane
	Molecular Function	Protein Binding
	Biological Process	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Neuromuscular Process Controlling Balance Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Development	Sensory Perception Of Sound Inner Ear Morphogenesis
Pathways			Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases		Usher syndrome (US)	Deafness, autosomal recessive
GWAS		Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
Interacting Genes		28 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MGST3 NRM SEC22B SLC34A3 SLC61A1 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15	28 interacting genes: ANKRD28 AQP6 CLRN1 CREB3L1 EBP FAM210B HMOX1 JAGN1 KRT34 KRTAP10-8 KRTAP12-3 MDFI NBPF19 NOTCH2NLA PLPP6 PLPPR2 RHBDD1 SEC22A SLC14A1 SUMO1 TLCD4 TMEM101 TMEM11 TMEM14B TMEM242 TMEM51 TMPPE VAPA
Entrez ID		7401	259236
HPRD ID		05905	06252
Ensembl ID		ENSG00000163646	ENSG00000181585
Uniprot IDs		P58418	A0A2R8YDZ8 Q8NEW7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane
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