TMIE and TMPPE

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMIE	TMPPE
Description		transmembrane inner ear	transmembrane protein with metallophosphoesterase domain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Membrane
	Molecular Function		Protein Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Sensory Perception Of Sound Inner Ear Morphogenesis
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases		Deafness, autosomal recessive
GWAS			Asthma ( 31619474 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		28 interacting genes: ANKRD28 AQP6 CLRN1 CREB3L1 EBP FAM210B HMOX1 JAGN1 KRT34 KRTAP10-8 KRTAP12-3 MDFI NBPF19 NOTCH2NLA PLPP6 PLPPR2 RHBDD1 SEC22A SLC14A1 SUMO1 TLCD4 TMEM101 TMEM11 TMEM14B TMEM242 TMEM51 TMPPE VAPA	35 interacting genes: AGTRAP ASGR2 CD79A CLDND2 CLRN1 CNR2 CYB561 FIS1 FXYD6 FXYD6-FXYD2 GPR152 IER3IP1 KCNJ6 KLRC1 LEMD1 MS4A1 PLLP PLPPR1 PNLIPRP1 REEP6 RETREG3 RTP2 SCN3B SFXN5 SLAMF6 SLC38A1 SMAGP SSMEM1 STX3 STX8 TMEM60 TMIE TRARG1 VAMP3 YIPF1
Entrez ID		259236	643853
HPRD ID		06252	18951
Ensembl ID		ENSG00000181585	ENSG00000188167
Uniprot IDs		A0A2R8YDZ8 Q8NEW7	Q6ZT21
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Plasma Membrane Organelle Membrane Fusion SNAP Receptor Activity Vesicle Fusion SNARE Complex Organelle Fusion Membrane Fusion Vesicle Docking Endoplasmic Reticulum Organization Organelle Localization By Membrane Tethering External Side Of Plasma Membrane Membrane Docking
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