CLRN1 and CANT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLRN1	CANT1
Description		clarin 1	calcium activated nucleotidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Microvillus Microtubule Cytoskeleton Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell Actin-based Cell Projection	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Golgi Cisterna Membrane Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	GDP Phosphatase Activity Calcium Ion Binding Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Protein Homodimerization Activity ADP Phosphatase Activity UDP Phosphatase Activity Metal Ion Binding
	Biological Process	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Neuromuscular Process Controlling Balance Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Development	Proteoglycan Biosynthetic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction
Pathways			Neutrophil degranulation
Drugs			Phosphomethylphosphonic acid guanosyl ester
Diseases		Usher syndrome (US)	Desbuquois syndrome
GWAS		Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
Interacting Genes		28 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MGST3 NRM SEC22B SLC34A3 SLC61A1 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15	4 interacting genes: CLRN1 FAM209A GOLPH3 GOLPH3L
Entrez ID		7401	124583
HPRD ID		05905	13003
Ensembl ID		ENSG00000163646	ENSG00000171302
Uniprot IDs		P58418	Q8WVQ1
PDB IDs			1S18 1S1D 2H2N 2H2U
Enriched GO Terms of Interacting Partners?		Membrane	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Targeting Establishment Of Protein Localization To Membrane Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery Equilibrioception Positive Regulation Of Protein Transport Regulation Of Protein Secretion Response To Rapamycin Golgi Vesicle Transport Auditory Receptor Cell Development Actin-based Cell Projection Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Lipid Binding Establishment Of Protein Localization To Organelle Golgi Ribbon Formation Cellular Response To Ether Inner Ear Receptor Cell Development Auditory Receptor Cell Stereocilium Organization Trans-Golgi Network Transport Vesicle Basal Part Of Cell Regulation Of Protein Transport Positive Regulation Of Protein Localization Leukocyte Tethering Or Rolling Response To Ether Localization Within Membrane Regulation Of Establishment Of Protein Localization
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