TMIE and TMEM242

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMIE	TMEM242
Description		transmembrane inner ear	transmembrane protein 242
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function		Protein Binding
	Biological Process	Sensory Perception Of Sound Inner Ear Morphogenesis	Mitochondrial Proton-transporting ATP Synthase Complex Assembly
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases		Deafness, autosomal recessive
GWAS			Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)
Interacting Genes		28 interacting genes: ANKRD28 AQP6 CLRN1 CREB3L1 EBP FAM210B HMOX1 JAGN1 KRT34 KRTAP10-8 KRTAP12-3 MDFI NBPF19 NOTCH2NLA PLPP6 PLPPR2 RHBDD1 SEC22A SLC14A1 SUMO1 TLCD4 TMEM101 TMEM11 TMEM14B TMEM242 TMEM51 TMPPE VAPA	36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1
Entrez ID		259236	729515
HPRD ID		06252
Ensembl ID		ENSG00000181585	ENSG00000215712
Uniprot IDs		A0A2R8YDZ8 Q8NEW7	Q9NWH2
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport
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