CLRN1 and DRAM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLRN1	DRAM1
Description		clarin 1	DNA damage regulated autophagy modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Microvillus Microtubule Cytoskeleton Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell Actin-based Cell Projection	Cytoplasm Lysosome Lysosomal Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Neuromuscular Process Controlling Balance Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Development	Autophagy Apoptotic Process Regulation Of Autophagy Cellular Response To Oxygen-glucose Deprivation
Pathways
Drugs
Diseases		Usher syndrome (US)
GWAS		Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)	Appendicular lean mass ( 33097823) Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Intracranial aneurysm ( 30823506) Shigella-associated diarrhea ( 33649051) Systemic lupus erythematosus ( 23273568 33272962)
Interacting Genes		28 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MGST3 NRM SEC22B SLC34A3 SLC61A1 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15	11 interacting genes: APP C1orf21 CD164L2 CLRN1 CREB3 EPS15 EVI2B GPR42 LRRC4C MS4A7 TIMMDC1
Entrez ID		7401	55332
HPRD ID		05905	07743
Ensembl ID		ENSG00000163646	ENSG00000136048
Uniprot IDs		P58418	Q8N682
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Regulation Of Monocyte Chemotaxis Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Deacetylase Activity Myeloid Cell Development Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Mononuclear Cell Migration Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Clathrin-coated Pit Positive Regulation Of Leukocyte Chemotaxis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization
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