UQCRFS1 and RELB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UQCRFS1	RELB
Gene Name		ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	v-rel avian reticuloendotheliosis viral oncogene homolog B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol I-kappaB/NF-kappaB Complex
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity Protein Complex Binding Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding
	Biological Process	Response To Hormone Respiratory Electron Transport Chain Response To Drug Cellular Metabolic Process Small Molecule Metabolic Process Response To Antibiotic Hydrogen Ion Transmembrane Transport	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response I-kappaB Kinase/NF-kappaB Signaling Antigen Processing And Presentation Circadian Regulation Of Gene Expression Response To Cytokine NIK/NF-kappaB Signaling Myeloid Dendritic Cell Differentiation T-helper 1 Cell Differentiation Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Osmotic Stress
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CYC1 RELB SOX5	25 interactors: BCL7A BUD31 CDK1 CTSL DPF2 EHMT2 EZH2 GSK3B HDAC6 KPNA2 KPNA6 MALT1 MT1M MTAP NFKB1 NFKB2 RELA SIN3A SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCE1 UQCRFS1 USP11
Entrez ID		7386	5971
HPRD ID		01874	06886
Ensembl ID			ENSG00000104856
Uniprot IDs		P47985	D6R992 Q01201
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mesenchymal Stem Cell Differentiation Regulation Of Timing Of Neuron Differentiation Regulation Of Mesenchymal Stem Cell Differentiation Response To Organic Substance T-helper 1 Cell Differentiation Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Myeloid Dendritic Cell Differentiation Myeloid Dendritic Cell Activation T-helper 1 Type Immune Response T-helper Cell Differentiation Cellular Response To Osmotic Stress Positive Regulation Of Chondrocyte Differentiation Transcription From RNA Polymerase II Promoter Dendritic Cell Differentiation CD4-positive, Alpha-beta T Cell Differentiation NIK/NF-kappaB Signaling CD4-positive, Alpha-beta T Cell Activation Positive Regulation Of Cartilage Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Stem Cell Differentiation Response To Glucagon I-kappaB Kinase/NF-kappaB Signaling Alpha-beta T Cell Differentiation Alpha-beta T Cell Activation T Cell Activation Involved In Immune Response Negative Regulation Of Gene Expression Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Oligodendrocyte Differentiation Circadian Regulation Of Gene Expression Response To Osmotic Stress Regulation Of Cartilage Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Respiratory Electron Transport Chain Myeloid Leukocyte Differentiation Electron Transport Chain Regulation Of Transcription From RNA Polymerase II Promoter	Nucleosome Disassembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Chromatin Organization Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated ATP-dependent Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Negative Regulation Of Gene Expression Chromosome Organization Positive Regulation Of Innate Immune Response Positive Regulation Of Cellular Metabolic Process Protein Complex Disassembly Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity NIK/NF-kappaB Signaling Regulation Of Metabolic Process Toll-like Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Innate Immune Response Positive Regulation Of Cellular Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Cellular Metabolic Process Immune Response-regulating Signaling Pathway Nucleosome Organization Response To Inorganic Substance Positive Regulation Of Transcription, DNA-templated Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Response To Hydrogen Peroxide Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Chromatin Assembly Or Disassembly Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?			balpha bbeta bepsilon biochemically casein ck complexed conjugation correspond crel ikappa ikappab ikk1 ikks indirectly initiates locate nonstimulated okadaic p100 p105 p90rsk1 pest phosphorylating purify rela s32 s36 serines
Tagcloud (Difference) ?			balpha bbeta bepsilon biochemically casein ck complexed conjugation correspond crel ikappa ikappab ikk1 ikks indirectly initiates locate nonstimulated okadaic p100 p105 p90rsk1 pest phosphorylating purify rela s32 s36 serines
Tagcloud (Intersection) ?