UQCRFS1 and CYC1

Number of citations of the paper that reports this interaction (PubMedID 2999105)
0

Data Source:
HPRD (in vitro)

		UQCRFS1	CYC1
Description		ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	cytochrome c1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Membrane Respiratory Chain Complex III	Nucleus Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex III
	Molecular Function	Protein Binding Quinol-cytochrome-c Reductase Activity Oxidoreductase Activity Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding	Protein Binding Quinol-cytochrome-c Reductase Activity Electron Transfer Activity Heme Binding Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex III Assembly Proton Transmembrane Transport	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Response To Glucagon Cellular Respiration Proton Transmembrane Transport
Pathways		Complex III assembly Complex III assembly Complex III assembly Complex III assembly Complex III assembly Respiratory electron transport Complex III assembly Complex III assembly Complex III assembly Complex III assembly Complex III assembly	Mitochondrial protein import Respiratory electron transport Complex III assembly Complex III assembly
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases
GWAS		Disease progression in age-related macular degeneration ( 29346644) Methadone dose in opioid dependence ( 28115739) Stroke ( 32693751)	Asthma ( 31959851) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		4 interacting genes: CYC1 HTR6 RELB SOX5	3 interacting genes: CYCS GRSF1 UQCRFS1
Entrez ID		7386	1537
HPRD ID		01874	00480
Ensembl ID		ENSG00000169021	ENSG00000179091
Uniprot IDs		P47985	P08574
PDB IDs		5XTE 5XTH 5XTI	5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?			Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Electron Transport Chain Aerobic Respiration Respiratory Electron Transport Chain Aerobic Electron Transport Chain Cellular Respiration Energy Derivation By Oxidation Of Organic Compounds Positive Regulation Of Mitochondrial RNA Catabolic Process Apoptosome Mitochondrion Quinol-cytochrome-c Reductase Activity Generation Of Precursor Metabolites And Energy Mitochondrial RNA Catabolic Process G-quadruplex RNA Binding Mitochondrial Matrix Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex III Assembly Mitochondrial Inner Membrane Ribonucleoprotein Granule Mitochondrial Electron Transport, Cytochrome C To Oxygen Morphogenesis Of Embryonic Epithelium 2 Iron, 2 Sulfur Cluster Binding Execution Phase Of Apoptosis Cytochrome Complex Assembly Mitochondrial RNA Metabolic Process Mitochondrial Nucleoid Electron Transfer Activity Iron-sulfur Cluster Binding
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