UGDH and ITGB1BP2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		UGDH	ITGB1BP2
Description		UDP-glucose 6-dehydrogenase	integrin subunit beta 1 binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome	Z Disc
	Molecular Function	Catalytic Activity UDP-glucose 6-dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Identical Protein Binding NAD Binding	Integrin Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding
	Biological Process	Gastrulation With Mouth Forming Second Glycosaminoglycan Biosynthetic Process UDP-glucuronate Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process Protein Hexamerization Neuron Development Chondroitin Sulfate Proteoglycan Biosynthetic Process	Signal Transduction Muscle Organ Development Centrosome Duplication
Pathways		Formation of the active cofactor, UDP-glucuronate
Drugs		NADH Copper
Diseases
GWAS		Haemorrhoidal disease ( 33888516) Response to tofacitinib treatment in psoriasis (herpes zoster) ( 33455090) Response to tofacitinib treatment in psoriasis (herpes zoster)(time to event) ( 33455090)
Interacting Genes		7 interacting genes: AK5 ANXA1 CDC42 ITGB1BP2 LINC00632 RAD51 UGT1A1	14 interacting genes: HSP90AA1 HSP90AB1 ITGB1 PPHLN1 PUM3 RARA RARG SGCA SH3GLB1 STAG2 TKT TTN UGDH WASL
Entrez ID		7358	26548
HPRD ID		04535	02271
Ensembl ID		ENSG00000109814	ENSG00000147166
Uniprot IDs		O60701	Q9UKP3
PDB IDs		2Q3E 2QG4 3ITK 3KHU 3PRJ 3PTZ 3TDK 3TF5 4EDF 4RJT 5TJH 5VR8 5W4X 6C4J 6C4K 6C58 6C5A 6C5Z 9DGZ
Enriched GO Terms of Interacting Partners?			Trachea Cartilage Development Glandular Epithelial Cell Development Telomerase Holoenzyme Complex Assembly Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Growth Plate Cartilage Development Regulation Of Protein Localization Melanosome Protein Kinase Regulator Activity Columnar/cuboidal Epithelial Cell Development Embryonic Camera-type Eye Development Regulation Of Plasma Membrane Organization Chaperone-mediated Protein Complex Assembly Chromosome Organization Telomere Maintenance Via Telomerase Histone Deacetylase Binding DNA Polymerase Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Retinoic Acid Receptor Signaling Pathway Face Development Protein Homodimerization Activity Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Protein-containing Complex Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex Negative Regulation Of Cartilage Development Skeletal Muscle Contraction Positive Regulation Of Protein Localization ATP-dependent Protein Folding Chaperone Cardiac Muscle Cell Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Protein Folding Muscle Contraction Positive Regulation Of Nitric Oxide Metabolic Process Extracellular Exosome Protein Tyrosine Kinase Binding Tau Protein Binding Supramolecular Fiber Organization Sarcomere Organization Regulation Of Myelination Anatomical Structure Morphogenesis CTP Binding DATP Binding Cellular Response To Heat Myoblast Fate Specification Cardiocyte Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?