HIRA and UBN1

Number of citations of the paper that reports this interaction (PMID 22401310)
3

Data Source:
BioGRID (pull down, affinity chromatography technology)

		HIRA	UBN1
Gene Name		histone cell cycle regulator	ubinuclein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm PML Body Protein Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Tight Junction PML Body
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Osteoblast Differentiation DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Gastrulation Anatomical Structure Morphogenesis Chromatin Modification Muscle Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription	DNA Replication-independent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Phosphatase Activity Viral Process Chromatin Modification
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence	DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ASF1A ASF1B CCNA2 CDK2 H3F3B HIRIP3 HIST1H2BD HIST1H2BK HIST2H2BE HNRNPD NFU1 PAX7 SUMO1 UBN1 UPF1	2 interactors: HIRA TJP1
Entrez ID		7290	29855
HPRD ID		02583	11660
Ensembl ID		ENSG00000100084	ENSG00000118900
Uniprot IDs		P54198	Q9NPG3
PDB IDs		2I32
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Chromatin Assembly Or Disassembly DNA Replication-independent Nucleosome Assembly Nucleosome Assembly Organelle Organization Chromatin Assembly Nucleosome Organization Protein-DNA Complex Assembly DNA Packaging DNA Conformation Change DNA Replication-dependent Nucleosome Assembly Chromatin Modification Cellular Macromolecular Complex Assembly Innate Immune Response In Mucosa Response To Stress Regulation Of Gene Silencing Cellular Response To DNA Damage Stimulus Antibacterial Humoral Response Regulation Of Gene Expression Antimicrobial Humoral Response Mucosal Immune Response Regulation Of Gene Expression, Epigenetic Protein Complex Assembly Regulation Of Transcription, DNA-templated DNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Repair Regulation Of RNA Metabolic Process Cellular Component Assembly Skeletal Muscle Satellite Cell Commitment Regulation Of Cellular Protein Metabolic Process Defense Response To Gram-positive Bacterium Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Mitotic DNA Integrity Checkpoint Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process PML Body Organization Positive Regulation Of DNA-dependent DNA Replication Initiation G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Localization To Nuclear Pore Positive Regulation Of Myoblast Proliferation	Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Magnetism Establishment Of Endothelial Intestinal Barrier Negative Regulation Of Vascular Permeability Establishment Of Endothelial Barrier Hippo Signaling Embryo Development Regulation Of Vascular Permeability DNA Replication-independent Nucleosome Assembly Blastocyst Formation Endothelial Cell Development Cellular Response To Glucose Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Endothelial Cell Differentiation Cellular Component Assembly Endothelium Development
Tagcloud ?		actively cabin1 caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn	asf1a cabin1 chaperone chromatin classes collaborates colocalize comprised coregulator correlates deposition enhancers functionally h3 hira immunoprecipitation incorporate insulator integrated interacting landscape nucleosome partners poised promoters remodeling sites underscoring weak
Tagcloud (Difference) ?		actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn	asf1a chaperone chromatin classes collaborates colocalize comprised coregulator correlates deposition enhancers functionally h3 immunoprecipitation incorporate insulator integrated interacting landscape partners poised promoters remodeling sites underscoring weak
Tagcloud (Intersection) ?		cabin1 hira nucleosome