UBN1 and HIRA

Number of citations of the paper that reports this interaction (PMID 22401310)
3

Data Source:
BioGRID (pull down, affinity chromatography technology)

		UBN1	HIRA
Gene Name		ubinuclein 1	histone cell cycle regulator
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Tight Junction PML Body	Nuclear Chromatin Nucleus Nucleoplasm PML Body Protein Complex Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding
	Biological Process	DNA Replication-independent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Phosphatase Activity Viral Process Chromatin Modification	Osteoblast Differentiation DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Gastrulation Anatomical Structure Morphogenesis Chromatin Modification Muscle Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence	DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: HIRA TJP1	15 interactors: ASF1A ASF1B CCNA2 CDK2 H3F3B HIRIP3 HIST1H2BD HIST1H2BK HIST2H2BE HNRNPD NFU1 PAX7 SUMO1 UBN1 UPF1
Entrez ID		29855	7290
HPRD ID		11660	02583
Ensembl ID		ENSG00000118900	ENSG00000100084
Uniprot IDs		Q9NPG3	P54198
PDB IDs			2I32
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Magnetism Establishment Of Endothelial Intestinal Barrier Negative Regulation Of Vascular Permeability Establishment Of Endothelial Barrier Hippo Signaling Embryo Development Regulation Of Vascular Permeability DNA Replication-independent Nucleosome Assembly Blastocyst Formation Endothelial Cell Development Cellular Response To Glucose Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Endothelial Cell Differentiation Cellular Component Assembly Endothelium Development	Chromatin Organization Chromosome Organization Chromatin Assembly Or Disassembly DNA Replication-independent Nucleosome Assembly Nucleosome Assembly Organelle Organization Chromatin Assembly Nucleosome Organization Protein-DNA Complex Assembly DNA Packaging DNA Conformation Change DNA Replication-dependent Nucleosome Assembly Chromatin Modification Cellular Macromolecular Complex Assembly Innate Immune Response In Mucosa Response To Stress Regulation Of Gene Silencing Cellular Response To DNA Damage Stimulus Antibacterial Humoral Response Regulation Of Gene Expression Antimicrobial Humoral Response Mucosal Immune Response Regulation Of Gene Expression, Epigenetic Protein Complex Assembly Regulation Of Transcription, DNA-templated DNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process DNA Repair Regulation Of RNA Metabolic Process Cellular Component Assembly Skeletal Muscle Satellite Cell Commitment Regulation Of Cellular Protein Metabolic Process Defense Response To Gram-positive Bacterium Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Mitotic DNA Damage Checkpoint Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Mitotic DNA Integrity Checkpoint Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process PML Body Organization Positive Regulation Of DNA-dependent DNA Replication Initiation G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Localization To Nuclear Pore Positive Regulation Of Myoblast Proliferation
Tagcloud ?		asf1a cabin1 chaperone chromatin classes collaborates colocalize comprised coregulator correlates deposition enhancers functionally h3 hira immunoprecipitation incorporate insulator integrated interacting landscape nucleosome partners poised promoters remodeling sites underscoring weak	actively cabin1 caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Difference) ?		asf1a chaperone chromatin classes collaborates colocalize comprised coregulator correlates deposition enhancers functionally h3 immunoprecipitation incorporate insulator integrated interacting landscape partners poised promoters remodeling sites underscoring weak	actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic impacts imply inheritance occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Intersection) ?		cabin1 hira nucleosome