AKAP9 and TUBGCP3

Number of citations of the paper that reports this interaction (PMID 12221128)
59

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		AKAP9	TUBGCP3
Gene Name		A kinase (PRKA) anchor protein 9	tubulin, gamma complex associated protein 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Golgi Apparatus Centrosome Cytosol Cytoskeleton Voltage-gated Potassium Channel Complex Ciliary Basal Body Intracellular Membrane-bounded Organelle	Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Membrane
	Molecular Function	Receptor Binding Protein Binding Potassium Channel Regulator Activity Protein Complex Scaffold Ion Channel Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Signal Transduction Synaptic Transmission Spermatogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Sertoli Cell Development Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cellular Response To CAMP Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Microtubule Nucleation Single Fertilization
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition CREB phosphorylation through the activation of Ras Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of NMDA receptor upon glutamate binding and postsynaptic events Loss of Nlp from mitotic centrosomes CREB phosphorylation through the activation of CaMKII Centrosome maturation Mitotic G2-G2/M phases Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Recruitment of mitotic centrosome proteins and complexes Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses	G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS			Glycated hemoglobin levels ( 20858683)
Protein-Protein Interactions		43 interactors: BLZF1 C1orf94 CALM1 CALM2 CALM3 CCP110 CDC5L CEP55 CLIC1 CSNK1D CSNK1E DISC1 FNBP1 GRIN1 HNRNPM IKZF3 KCNQ1 KDM1A MAGEA6 MAGED1 PCNT PKN1 PPP1CA PPP2R1B PPP2R3A PRDM14 PRKAR2A PRKAR2B PRKCE SAMD3 SSX2 SUV39H2 TACC3 TDP2 THAP1 TNIK TRIP10 TSG101 TSNAX TUBGCP3 USHBP1 USO1 WAC	5 interactors: AKAP9 IMMT PCNT TUBG1 TUBG2
Entrez ID		10142	10426
HPRD ID		04921	10289
Ensembl ID		ENSG00000127914	ENSG00000126216
Uniprot IDs		Q5GIA7 Q6PJH3 Q99996	Q96CW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Organelle Organization Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity G2/M Transition Of Mitotic Cell Cycle Regulation Of Cytokinesis Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin Signaling Pathway Regulation Of Signaling Energy Reserve Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Amphetamine Blood Coagulation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Protein Metabolic Process Hemostasis Regulation Of Circadian Rhythm Cell Cycle Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Transporter Activity Response To Fibroblast Growth Factor Positive Regulation Of Protein Kinase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Detection Of Calcium Ion Negative Regulation Of Ion Transmembrane Transport Response To Amine Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Cell Cycle Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Transmembrane Transport Mitotic Cell Cycle Positive Regulation Of Transferase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Mitotic Cell Cycle Microtubule Nucleation Microtubule Polymerization Cell Cycle Process Cytoplasmic Microtubule Organization Microtubule Polymerization Or Depolymerization Cell Cycle Microtubule Cytoskeleton Organization Protein Polymerization Spindle Organization Microtubule-based Process Cytoskeleton Organization Organelle Organization Cellular Protein Complex Assembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Meiotic Spindle Organization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Mitochondrial Calcium Ion Homeostasis Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Component Assembly Sertoli Cell Development Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Sertoli Cell Differentiation Cellular Macromolecular Complex Assembly Regulation Of Potassium Ion Transmembrane Transport Olfactory Bulb Development Cerebellar Cortex Morphogenesis Positive Regulation Of Transport Brain Morphogenesis Olfactory Lobe Development Cardiac Conduction Cellular Response To CAMP Positive Regulation Of Ion Transmembrane Transporter Activity Cerebellum Morphogenesis Hindbrain Morphogenesis Response To Cold Positive Regulation Of Transporter Activity
Tagcloud ?		akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?