TRPC5 and ENKUR

Number of citations of the paper that reports this interaction (PubMedID 15385169)
0

Data Source:
BioGRID (pull down)

		TRPC5	ENKUR
Description		transient receptor potential cation channel subfamily C member 5	enkurin, TRPC channel interacting protein
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GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Growth Cone Cation Channel Complex Calcium Channel Complex Neuronal Cell Body Presynapse	Acrosomal Vesicle Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Microtubule Cytoskeleton Motile Cilium Sperm Flagellum Cell Projection Sperm Principal Piece 9+0 Motile Cilium 9+2 Motile Cilium Axonemal B Tubule Inner Sheath
	Molecular Function	Actin Binding Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity Clathrin Binding Actinin Binding Metal Ion Binding ATPase Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding Calmodulin Binding SH3 Domain Binding
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Nervous System Development Positive Regulation Of Cell Population Proliferation Neuron Differentiation Monoatomic Ion Transmembrane Transport Positive Regulation Of Neuron Differentiation Positive Regulation Of Axon Extension Negative Regulation Of Dendrite Morphogenesis Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Transmembrane Transport Calcium Ion Transmembrane Transport Phosphatidylserine Exposure On Apoptotic Cell Surface Regulation Of Membrane Hyperpolarization	Flagellated Sperm Motility Establishment Of Left/right Asymmetry
Pathways		TRP channels Role of second messengers in netrin-1 signaling
Drugs
Diseases
GWAS		Smoking behavior ( 19247474)
Interacting Genes		9 interacting genes: DRD2 ENKUR ITPR3 MX1 NHERF1 STMN2 STMN3 TRPC1 TRPC4	6 interacting genes: CFAP45 LRRK1 LRRK2 PIK3R1 PIK3R2 TRPC5
Entrez ID		7224	219670
HPRD ID		02273	12583
Ensembl ID		ENSG00000072315	ENSG00000151023
Uniprot IDs		Q9UL62	A0A087WUX1 Q8TC29
PDB IDs		6YSN 7D4P 7D4Q 7E4T 7WDB 7X6C 7X6I 8GVW 8GVX	7UNG 8J07
Enriched GO Terms of Interacting Partners?		Inositol 1,4,5 Trisphosphate Binding Acid Secretion Inorganic Ion Homeostasis Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Calcium Ion Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Metal Ion Transport Calcium Channel Activity Store-operated Calcium Channel Activity Gamma-aminobutyric Acid Transport Monoatomic Cation Transport Cation Channel Complex Microtubule Depolymerization Regulation Of Sequestering Of Calcium Ion Chemical Homeostasis G Protein-coupled Dopamine Receptor Signaling Pathway Monoatomic Ion Transport Monoatomic Ion Channel Activity Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Calcium Ion Homeostasis Intracellular Chemical Homeostasis Protein Depolymerization Microtubule Polymerization Or Depolymerization Transmembrane Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transmembrane Transport Cellular Homeostasis Carboxylic Acid Transport Organic Acid Transport Homeostatic Process Inorganic Ion Transmembrane Transport Regulation Of Cytosolic Calcium Ion Concentration Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Structural Constituent Of Presynaptic Actin Cytoskeleton Renal Phosphate Ion Absorption Tubulin Binding Monoatomic Ion Transmembrane Transport Regulation Of Sodium Ion Transport Response To Metal Ion Microtubule-based Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Organic Anion Transport Regulation Of Metal Ion Transport G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Phenol-containing Compound Metabolic Process Apical Part Of Cell	Phosphatidylinositol 3-kinase Complex, Class IA 1-phosphatidylinositol-3-kinase Regulator Activity Phosphatidylinositol 3-kinase Regulatory Subunit Binding Intracellular Chemical Homeostasis Homeostatic Process Cellular Homeostasis Clathrin Binding GTPase Activator Activity Positive Regulation Of Protein Import Into Nucleus Regulation Of Intracellular Transport Phosphotyrosine Residue Binding Positive Regulation Of Transport Chemical Homeostasis Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Tumor Necrosis Factor Production Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Insulin Stimulus Regulation Of Stress Fiber Assembly Positive Regulation Of Intracellular Protein Transport Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Phosphatase Binding Intracellular Glucose Homeostasis Positive Regulation Of Protein Localization To Nucleus Insulin Receptor Signaling Pathway Regulation Of Neurotransmitter Secretion G Protein-coupled Glycine Receptor Activity Positive Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Cellular Localization B Cell Differentiation Regulation Of Establishment Of Protein Localization Regulation Of Cellular Component Organization Protein Import Into Nucleus Regulation Of Protein Localization To Plasma Membrane Regulation Of Nucleocytoplasmic Transport Kinase Regulator Activity Import Into Nucleus Perinuclear Endoplasmic Reticulum Membrane Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Protein Autoubiquitination
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