HNRNPA0 and PRR3

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		HNRNPA0	PRR3
Description		heterogeneous nuclear ribonucleoprotein A0	proline rich 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Synapse Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Kinase Binding MRNA 3'-UTR AU-rich Region Binding	RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Processing Inflammatory Response Response To Lipopolysaccharide 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Itch intensity from mosquito bite ( 28199695) Neuroticism ( 29255261)
Interacting Genes		98 interacting genes: CCT3 CEBPA CEP55 CIRBP CLK1 DDX5 FILNC1 HNRNPF HNRNPH2 HNRNPH3 HNRNPK IL7R KHDRBS2 MAPK6 MAPKAPK2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MTNR1A MTNR1B NEIL3 NKX3-1 PRR3 RBM3 SLU7 SNRPA SRSF1 SUMO2 UBC	25 interacting genes: APOBEC3C ASF1A BCL2L2-PABPN1 CCDC57 CLP1 DMRTB1 EXOSC8 HNRNPA0 KHDRBS2 KHDRBS3 KLF1 KRT31 KRTAP6-2 KRTAP6-3 MYPOP NXF1 PSMA3 RAMAC RBM3 RBMX RBMY1A1 RBMY1F RBMY1J SNRPA TLE5
Entrez ID		10949	80742
HPRD ID		17112	17915
Ensembl ID		ENSG00000177733	ENSG00000204576
Uniprot IDs		Q13151	B3KQA4 P79522 Q96QB9
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Cytokine Production Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Regulation Of Metabolic Process Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Migration Extracellular Space Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signal Transduction	Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing MRNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Processing Nucleic Acid Binding Positive Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Binding RNA Metabolic Process Spliceosomal Complex Nucleic Acid Metabolic Process MRNA Binding Positive Regulation Of MRNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Splicing Nucleus Nucleobase-containing Compound Metabolic Process Nucleoplasm Regulation Of RNA Metabolic Process Identical Protein Binding Regulation Of Gene Expression MRNA 3'-UTR AU-rich Region Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Gene Expression Intermediate Filament ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex RNA 5'-cap (guanine-N7)-methylation Regulation Of Macromolecule Metabolic Process Global Gene Silencing By MRNA Cleavage U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Supraspliceosomal Complex Keratinization
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