TNP1 and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TNP1	SDCBP2
Description		transition protein 1	syndecan binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleosome Male Germ Cell Nucleus Nucleus Chromosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Single Strand Break Repair Nucleosome Disassembly Chromatin Remodeling Spermatogenesis Spermatid Development Spermatid Nucleus Differentiation Spermatid Nucleus Elongation Positive Regulation Of Protein Processing Sexual Reproduction Cell Differentiation Flagellated Sperm Motility Heterochromatin Formation Sperm DNA Decondensation Sperm DNA Condensation Negative Regulation Of DNA-templated Transcription	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163) Glomerular filtration rate ( 29403010) Height ( 25282103 31562340) Hypothyroidism ( 27182965) Mitral valve prolapse ( 26301497) Permanent tooth development ( 21931568) Pulse pressure ( 27841878) Thyroid stimulating hormone levels ( 32769997)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CSNK2A1 DVL3 PPARA PPARD PPARG PRKACA PRKACB PRKACG PRKCA SDCBP2	66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		7141	27111
HPRD ID		01830	18032
Ensembl ID		ENSG00000118245	ENSG00000125775
Uniprot IDs		P09430 Q4ZG82	Q9H190
PDB IDs
Enriched GO Terms of Interacting Partners?		CAMP-dependent Protein Kinase Activity Negative Regulation Of Cholesterol Storage CAMP-dependent Protein Kinase Complex High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Intracellular Signal Transduction Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis Negative Regulation Of Lipid Storage Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Negative Regulation Of MiRNA Transcription Renal System Process Multicellular Organismal-level Water Homeostasis Cellular Response To Fluid Shear Stress Protein Serine Kinase Activity Regulation Of Biological Quality Positive Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Protein Secretion Positive Regulation Of Hormone Secretion Positive Regulation Of Small Molecule Metabolic Process Ciliary Base Response To Fluid Shear Stress Protein Serine/threonine Kinase Activity Regulation Of Lipid Storage Regulation Of Intracellular Signal Transduction Nuclear Receptor Activity Response To Nutrient Levels Signal Transduction Protein Kinase Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cardiac Muscle Hypertrophy Cellular Response To Stress Regulation Of Muscle System Process Positive Regulation Of Protein Transport Regulation Of MiRNA Transcription Cellular Response To Nutrient Levels Regulation Of Hormone Secretion Regulation Of Protein Secretion Positive Regulation Of Insulin Secretion Regulation Of MiRNA Metabolic Process Regulation Of Body Fluid Levels Kinase Activity Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Secretion By Cell Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Fatty Acid Metabolic Process	Protein Binding
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