C1QC and FKBP2

Number of citations of the paper that reports this interaction (PMID 15353007)
0

Data Source:
HPRD (two hybrid, in vitro)

		C1QC	FKBP2
Gene Name		complement component 1, q subcomponent, C chain	FK506 binding protein 2, 13kDa
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Extracellular Vesicular Exosome Blood Microparticle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function		Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Classical Pathway Negative Regulation Of Granulocyte Differentiation Innate Immune Response Negative Regulation Of Macrophage Differentiation	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding
Pathways		Classical antibody-mediated complement activation Creation of C4 and C2 activators Complement cascade Initial triggering of complement Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: C1QA C1QB FKBP2 PTX3	13 interactors: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2
Entrez ID		714	2286
HPRD ID		00395	01742
Ensembl ID		ENSG00000159189	ENSG00000173486
Uniprot IDs		P02747	P26885 Q53XJ5
PDB IDs		1PK6 2JG8 2JG9 2WNU 2WNV	2PBC
Enriched GO Terms of Interacting Partners?		Innate Immune Response Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Protein Activation Cascade Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Negative Regulation Of Exo-alpha-sialidase Activity Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Humoral Immune Response Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Immune Response Defense Response Leukocyte Mediated Immunity Adaptive Immune Response Response To Yeast Opsonization Negative Regulation Of Glycoprotein Metabolic Process Negative Regulation Of Viral Entry Into Host Cell Immune System Process Dopaminergic Neuron Differentiation Regulation Of Viral Entry Into Host Cell Sensory Organ Development Positive Regulation Of Immune Response Lens Morphogenesis In Camera-type Eye Interaction With Symbiont Lens Fiber Cell Differentiation Response To Fungus Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Immune Response Positive Regulation Of Phagocytosis Positive Regulation Of Immune System Process Regulation Of Nitric Oxide Biosynthetic Process Chaperone-mediated Protein Folding Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Stress Regulation Of Phagocytosis Negative Regulation Of Viral Process Protein Peptidyl-prolyl Isomerization Midbrain Development Positive Regulation Of Reactive Oxygen Species Metabolic Process Lens Development In Camera-type Eye Regulation Of Immune System Process Positive Regulation Of Endocytosis	Ras Protein Signal Transduction Cortical Actin Cytoskeleton Organization Regulation Of Protein Metabolic Process Establishment Of Protein Localization Endomembrane System Organization Cortical Cytoskeleton Organization Small GTPase Mediated Signal Transduction Protein Localization Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Cellular Protein Localization Immune System Process Negative Regulation Of Apolipoprotein Binding Positive Regulation Of Protein Glycosylation In Golgi Vesicle-mediated Transport Exocytosis Protein Localization To Membrane Cellular Localization Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Regulation Of Intracellular Transport Neurotransmitter Secretion Synaptic Vesicle Transport Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Eosinophil Degranulation Regulation Of Cellular Localization Intracellular Signal Transduction Regulation Of Golgi Inheritance Positive Regulation Of Protein Glycosylation Secretion By Cell Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Neurotransmitter Levels Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Regulation Of Protein Binding Protein Localization To Plasma Membrane Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Protein Export From Nucleus Neurotransmitter Transport Actin Cytoskeleton Organization Organelle Organization Regulation Of Golgi Organization Protein K6-linked Ubiquitination Negative Regulation Of Granulocyte Differentiation
Tagcloud ?		antioxidative atf3 atf4 atf5 axonal believe c1qa c1qb c57bl chac1 chop concurrently crush defense egr1 ganglion glaucoma hmox1 ocular onc optic retinal retinas rgc seq sham srxn1 transcriptome trb3
Tagcloud (Difference) ?		antioxidative atf3 atf4 atf5 axonal believe c1qa c1qb c57bl chac1 chop concurrently crush defense egr1 ganglion glaucoma hmox1 ocular onc optic retinal retinas rgc seq sham srxn1 transcriptome trb3
Tagcloud (Intersection) ?