HNF4G and PNRC2

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNF4G	PNRC2
Gene Name		hepatocyte nuclear factor 4, gamma	proline-rich nuclear receptor coactivator 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Cytoplasmic MRNA Processing Body Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Zinc Ion Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Intracellular Receptor Signaling Pathway Endocrine Pancreas Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Transcription, DNA-templated Regulation Of Transcription, DNA-templated Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways		Regulation of beta-cell development Generic Transcription Pathway Regulation of gene expression in beta cells Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Body mass index ( 20935630) Breast cancer ( 23535729) Obesity ( 23563607) Urate levels ( 23263486)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		14 interactors: COPS5 EIF3I GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 RANBP9 SRC TNNI2	20 interactors: AR DCP1A ESR1 ESR2 ESRRA ESRRG GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SF1 SPAG9 XRCC6 ZBTB16 ZBTB48
Entrez ID		3174	55629
HPRD ID		06909	17871
Ensembl ID		ENSG00000164749	ENSG00000189266
Uniprot IDs		F1D8Q4 Q14541	Q9NPJ4
PDB IDs		1LV2	4B6H
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Response To Progesterone Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose Peptidyl-cysteine S-trans-nitrosylation Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling RNA Metabolic Process Cellular Response To Progesterone Stimulus Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cellular Response To Drug Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Targeting To Mitochondrion Exosomal Secretion Response To Steroid Hormone Regulation Of Protein Kinase B Signaling Peptidyl-cysteine S-nitrosylation Positive Regulation Of Integrin Activation Positive Regulation Of Podosome Assembly Regulation Of Response To Drug Negative Regulation Of Mitochondrial Depolarization Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Positive Regulation Of Female Receptivity Regulation Of Podosome Assembly Cellular Response To Hormone Stimulus Male Mating Behavior Regulation Of Caveolin-mediated Endocytosis Mammary Gland Development	Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Cellular Response To Hormone Stimulus Transcription From RNA Polymerase II Promoter Response To Lipid Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Organ Development Response To Organic Substance Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Developmental Process Involved In Reproduction Prostate Gland Development Sex Differentiation Multicellular Organismal Development Anatomical Structure Development Regulation Of Metabolic Process
Tagcloud ?		5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Difference) ?		5th adcy9 ancestry broader classes etiological exploiting extremes generalizable gnat2 h6pd height hip hs6st3 igfbp4 influencing loci mrps33p4 obesity overlap percentiles ppp2r2a rptor rsrc1 tails trait traits waist zzz3	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Intersection) ?