YIPF1 and ASGR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIPF1	ASGR2
Description		Yip1 domain family member 1	asialoglycoprotein receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Nucleoplasm Endosome Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Plasma Membrane Endomembrane System Membrane Transport Vesicle Late Endosome Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding	Asialoglycoprotein Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Fucose Binding
	Biological Process	Vesicle-mediated Transport	Endocytosis Immune Response Cell Surface Receptor Signaling Pathway
Pathways			Asparagine N-linked glycosylation
Drugs			Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases
GWAS		Nonalcoholic fatty liver disease ( 22719876)	Congenital heart disease (maternal effect) ( 28468790) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Total cholesterol levels ( 30275531)
Interacting Genes		35 interacting genes: APCDD1L AQP6 ASGR2 CLDN5 CMTM2 CNR2 EBP ERGIC3 F2RL1 FFAR3 GPR152 GPR42 GPRC5D KCNJ6 LEPROT LINC00839 LMNA RETREG3 RNF5 SIGLEC12 SLC10A6 SLC18A1 SLC35G1 SLC71A2 SLC7A8 TIMMDC1 TLCD4 TMEM14B TMEM248 TMPPE TMX2 TVP23B VMA21 YIPF6 ZDHHC7	50 interacting genes: ADAM33 ADIPOQ AIG1 ASGR1 ATP6V0C BET1 CD53 CERS2 CLEC17A CLEC7A EMP1 F8 FA2H FATE1 GLP1R GLUD1 HES1 HMOX2 IL1RL1 LAT LNPEP MCEMP1 MMD2 MROH5 MS4A13 NRG1 ORMDL1 PLN PLP2 PMP22 RPRM SEC22A SLC35A1 SLC35B2 SMIM3 SNCA STX8 TFRC TMEM140 TMEM60 TMEM86B TMPPE TRAM1L1 TSPO2 UBIAD1 UPK2 VAMP5 VKORC1 VTI1B YIPF1
Entrez ID		54432	433
HPRD ID		13147	00152
Ensembl ID		ENSG00000058799	ENSG00000161944
Uniprot IDs		Q9Y548	P07307 Q7Z4G9
PDB IDs			8URF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum G Protein-coupled Receptor Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Protein Binding Regulation Of Mitotic Cell Cycle, Embryonic Pancreas Development Fucose Binding Regulation Of Secondary Heart Field Cardioblast Proliferation Endomembrane System Chloride Channel Inhibitor Activity Vesicle Fusion With Golgi Apparatus Plasma Membrane Pattern Recognition Receptor Activity Perinuclear Region Of Cytoplasm Regulation Of Calcium Ion Import Negative Regulation Of Gliogenesis Regulation Of Cardioblast Proliferation Bleb Assembly Positive Regulation Of Phosphate Metabolic Process SNARE Complex Organelle Membrane Identical Protein Binding Nephron Tubule Formation Negative Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Protein Autophosphorylation Nephron Tubule Morphogenesis Cellular Response To Epinephrine Stimulus Vitamin K Metabolic Process Kidney Morphogenesis Positive Regulation Of Kinase Activity Negative Regulation Of Calcium Ion Import Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Monocyte Chemotactic Protein-1 Production
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