YIPF1 and SIGLEC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YIPF1	SIGLEC12
Description		Yip1 domain family member 1	sialic acid binding Ig like lectin 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Nucleoplasm Endosome Golgi Apparatus Golgi Medial Cisterna Trans-Golgi Network Plasma Membrane Endomembrane System Membrane Transport Vesicle Late Endosome Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Vesicle-mediated Transport	Cell Adhesion
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Nonalcoholic fatty liver disease ( 22719876)
Interacting Genes		35 interacting genes: APCDD1L AQP6 ASGR2 CLDN5 CMTM2 CNR2 EBP ERGIC3 F2RL1 FFAR3 GPR152 GPR42 GPRC5D KCNJ6 LEPROT LINC00839 LMNA RETREG3 RNF5 SIGLEC12 SLC10A6 SLC18A1 SLC35G1 SLC71A2 SLC7A8 TIMMDC1 TLCD4 TMEM14B TMEM248 TMPPE TMX2 TVP23B VMA21 YIPF6 ZDHHC7	17 interacting genes: ACSF2 ADIPOQ ATP5PF CDIPT CLEC4G CMAS CTSA DNAJC30 IL1RL1 MGST1 PLPP6 PLPPR2 PTCH1 PTPN11 PTPN6 TMPRSS4 YIPF1
Entrez ID		54432	89858
HPRD ID		13147	16195
Ensembl ID		ENSG00000058799	ENSG00000254521
Uniprot IDs		Q9Y548	Q96PQ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum G Protein-coupled Receptor Activity	Regulation Of Neutrophil Activation Phosphate-containing Compound Metabolic Process Dephosphorylation Organophosphate Metabolic Process Negative Regulation Of Neutrophil Activation Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Adaptive Immune Response Negative Regulation Of Cell-cell Adhesion Negative Regulation Of T Cell Proliferation Neutrophil Activation Involved In Immune Response Brain Development Phosphatidate Phosphatase Activity Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Immune System Process Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Cell Adhesion Platelet Formation Megakaryocyte Development Positive Regulation Of Viral Life Cycle Positive Regulation Of Cholesterol Efflux Regulation Of Lipid Transport Negative Regulation Of T Cell Activation Negative Regulation Of Cytokine Production Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Cell Activation Lipid Modification Cellular Response To Lipid Hydroperoxide Negative Regulation Of Cell Population Proliferation Neural Plate Axis Specification Regulation Of Cholesterol Efflux Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Cholesterol Transport Reproductive Structure Development Cytokine-mediated Signaling Pathway Regulation Of T Cell Proliferation Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Cell Activation Negative Regulation Of Lymphocyte Activation Regulation Of Tumor Necrosis Factor Production T Cell Costimulation Regulation Of Cytokine-mediated Signaling Pathway Epididymis Development Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Positive Regulation Of D-glucose Import Positive Regulation Of D-glucose Transmembrane Transport
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