CLDN3 and POM121

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CLDN3	POM121
Gene Name		claudin 3	POM121 transmembrane nucleoporin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Tight Junction Integral Component Of Membrane Lateral Plasma Membrane Extracellular Vesicular Exosome	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Nuclear Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Structural Molecule Activity Identical Protein Binding
	Biological Process	Response To Hypoxia Epithelial Cell Morphogenesis Signal Transduction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS			Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		7 interactors: APP CLDN1 CLDN5 POM121 PRKACA TJP1 WNK4	21 interactors: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CLDN3 COL4A3BP FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6
Entrez ID		1365	9883
HPRD ID		04219	11448
Ensembl ID		ENSG00000165215	ENSG00000196313
Uniprot IDs		O15551 Q75L79	Q96HA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemical Homeostasis Homeostatic Process Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Multicellular Organismal Water Homeostasis Cellular Response To Glucose Stimulus Water Homeostasis Nuclear Envelope Organization Cell Adhesion Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Cell-cell Signaling Involved In Cell-cell Junction Organization Positive Regulation Of Dense Core Granule Biogenesis Renal System Process Regulation Of Glucose Transport Cellular Chemical Homeostasis Multicellular Organismal Development Ion Homeostasis Anatomical Structure Development Regulation Of Body Fluid Levels Positive Regulation Of Mitotic Cell Cycle Cell-cell Junction Assembly Nucleus Organization Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Response To Glucose Regulation Of Protein Binding Cell Maturation Cellular Homeostasis Distal Tubule Morphogenesis Collateral Sprouting In Absence Of Injury Developmental Process Renal Sodium Ion Absorption Response To Magnetism Response To Carbohydrate Platelet Activation Collateral Sprouting Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Axon Midline Choice Point Recognition Cell Junction Assembly Membrane Organization Glucose Homeostasis Pathogenesis Regulation Of Peptidyl-tyrosine Phosphorylation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cell Cycle Process Peptidyl-serine Autophosphorylation	Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Negative Regulation Of Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Signaling Regulation Of Microtubule-based Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Histone Methylation Mitotic Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Regulation Of Signaling Regulation Of Protein Localization To Nucleus Regulation Of Centrosome Duplication Regulation Of Chromosome Organization Regulation Of Histone Acetylation Cell Cycle Regulation Of Nucleocytoplasmic Transport Regulation Of Centrosome Cycle Signaling Regulation Of Histone Methylation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Schwann Cell Proliferation Cell Communication DNA Recombination Cellular Response To Stress Regulation Of Intracellular Protein Transport Regulation Of Signal Transduction Cell Cycle Process Positive Regulation Of Histone Modification Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Mucus Secretion Positive Regulation Of Histone H3-K9 Acetylation ER To Golgi Ceramide Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Signal Transduction Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Chromosome Organization Lung Goblet Cell Differentiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Transcription Factor Import Into Nucleus Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus
Tagcloud ?		anat asmt characterise circumventricular col11a1 cvos epcam ependyma ependymocytes lcm microdissection organum ovlt peculiar periventricular pineal ren1 sco sfo slc22a3 specialised subcommissural subfornical terminalis tph transcriptomes vasculosum ventricles vestigial	antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis
Tagcloud (Difference) ?		anat asmt characterise circumventricular col11a1 cvos epcam ependyma ependymocytes lcm microdissection organum ovlt peculiar periventricular pineal ren1 sco sfo slc22a3 specialised subcommissural subfornical terminalis tph transcriptomes vasculosum ventricles vestigial	antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis
Tagcloud (Intersection) ?