BANF1

Description		barrier to autointegration nuclear assembly factor 1
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GO Annotations	Cellular Component	Chromatin Condensed Chromosome Nucleus Nuclear Envelope Nucleoplasm Chromosome Cytoplasm Cytosol
	Molecular Function	DNA Binding Double-stranded DNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	DNA Repair Chromatin Organization Response To Oxidative Stress Mitotic Nuclear Membrane Reassembly Response To Virus Negative Regulation Of Protein ADP-ribosylation DNA Integration Negative Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Negative Regulation Of Viral Genome Replication Negative Regulation Of Innate Immune Response Chromosome Organization CGAS/STING Signaling Pathway Negative Regulation Of CGAS/STING Signaling Pathway
Pathways		Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32514006)
Novel Interacting Genes		2 novel interacting genes: RASSF1 SHANK2
Interacting Genes		5 interacting genes: CEBPA CRX EMD ERBIN TMPO
Entrez ID		8815
HPRD ID		04817
Ensembl ID		ENSG00000175334
Uniprot IDs		O75531
PDB IDs		1CI4 1QCK 2BZF 2EZX 2EZY 2EZZ 2ODG 6GHD 6RPR 6UNT 6URE 6URJ 6URK 6URL 6URN 6URR 6URZ 6US0 6US1 6US7 6USB 6USD 6USI 7ABM 7NDY 7Z21 9J8M 9J8N 9J8O
Enriched GO Terms of Interacting Partners?		Nuclear Membrane Nuclear Inner Membrane CHOP-C/EBP Complex Response To Tumor Necrosis Factor Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex RNA Polymerase II Transcription Regulator Complex System Process TMEM240-body Synaptic Receptor Adaptor Activity Negative Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway ErbB-2 Class Receptor Binding Basal Protein Localization
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