SEC62 and CIC

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SEC62	CIC
Description		SEC62 preprotein translocation factor	capicua transcriptional repressor
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane	Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Protein Binding Signaling Receptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding
	Biological Process	Cotranslational Protein Targeting To Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Transport Post-translational Protein Targeting To Membrane, Translocation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of DNA-templated Transcription Lung Alveolus Development
Pathways
Drugs
Diseases
GWAS		Cadmium levels ( 26025379)	Bitter alcoholic beverage consumption ( 31046077) Neutrophil count ( 32888494)
Interacting Genes		8 interacting genes: CIC CTNNB1 GABARAP GABARAPL1 MAP1LC3A OGT SEC63 ZNF24	13 interacting genes: ATXN1 CPAP CSNK2B GABPB1 GOLGA2 GTPBP3 NFYC PICK1 POLR1H PYCR2 SEC62 SETD2 TRIM22
Entrez ID		7095	23152
HPRD ID		03706	10831
Ensembl ID		ENSG00000008952	ENSG00000079432
Uniprot IDs		Q99442	A0A0A0MQR4 I3L2J0 Q96RK0
PDB IDs		7BRT	2M41 4J2J 4J2L 6JRP 6KZG 6KZH
Enriched GO Terms of Interacting Partners?		Mitophagy Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Phosphatidylethanolamine Binding Macroautophagy Autophagosome Maturation Autophagosome Membrane Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding Autophagy Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding GABA Receptor Binding Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein-containing Complex Disassembly Response To Nutrient Levels Vacuole Organization Regulation Of Protein Localization To Synapse Cellular Response To Starvation Regulation Of Protein Ubiquitination Regulation Of Receptor Localization To Synapse Regulation Of Rac Protein Signal Transduction Response To Starvation Regulation Of Post-translational Protein Modification Beta-tubulin Binding Organelle Assembly Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Sec62/Sec63 Complex Microtubule Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Negative Regulation Of Post-translational Protein Modification Catabolic Process Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation
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