SEC62 and SEC63

Number of citations of the paper that reports this interaction (PubMedID 10799540)
0

Data Source:
HPRD (in vitro)

		SEC62	SEC63
Description		SEC62 preprotein translocation factor	SEC63 protein translocation regulator
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sec62/Sec63 Complex
	Molecular Function	Protein Binding Signaling Receptor Activity	RNA Binding Protein Binding Protein Transmembrane Transporter Activity Signaling Receptor Activity
	Biological Process	Cotranslational Protein Targeting To Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Transport Post-translational Protein Targeting To Membrane, Translocation	Liver Development Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Transport Post-translational Protein Targeting To Membrane, Translocation Nitrogen Cycle Metabolic Process
Pathways
Drugs
Diseases			Polycystic liver disease
GWAS		Cadmium levels ( 26025379)	Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction ( 32080893)
Interacting Genes		8 interacting genes: CIC CTNNB1 GABARAP GABARAPL1 MAP1LC3A OGT SEC63 ZNF24	5 interacting genes: HSPA5 MEOX2 RNF10 SEC61B SEC62
Entrez ID		7095	11231
HPRD ID		03706	09783
Ensembl ID		ENSG00000008952	ENSG00000025796
Uniprot IDs		Q99442	A0A0S2Z5M1 Q9UGP8
PDB IDs		7BRT
Enriched GO Terms of Interacting Partners?		Mitophagy Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Phosphatidylethanolamine Binding Macroautophagy Autophagosome Maturation Autophagosome Membrane Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding Autophagy Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding GABA Receptor Binding Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein-containing Complex Disassembly Response To Nutrient Levels Vacuole Organization Regulation Of Protein Localization To Synapse Cellular Response To Starvation Regulation Of Protein Ubiquitination Regulation Of Receptor Localization To Synapse Regulation Of Rac Protein Signal Transduction Response To Starvation Regulation Of Post-translational Protein Modification Beta-tubulin Binding Organelle Assembly Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Sec62/Sec63 Complex Microtubule Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Negative Regulation Of Post-translational Protein Modification Catabolic Process Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation	Post-translational Protein Targeting To Membrane, Translocation Intracellular Protein Transmembrane Transport Protein Transmembrane Transport ERAD Pathway Proteasomal Protein Catabolic Process Ribosome Binding Regulation Of Protein Folding In Endoplasmic Reticulum Intracellular Protein Transport Endoplasmic Reticulum Sec Complex Protein Catabolic Process Cerebellum Structural Organization Proteolysis Involved In Protein Catabolic Process Regulation Of ATF6-mediated Unfolded Protein Response Epidermal Growth Factor Binding Regulation Of Protein Folding Maintenance Of Protein Localization In Endoplasmic Reticulum Macromolecule Catabolic Process PERK-mediated Unfolded Protein Response Response To Endoplasmic Reticulum Stress ER Overload Response Endoplasmic Reticulum Membrane Endoplasmic Reticulum Chaperone Complex Negative Regulation Of PERK-mediated Unfolded Protein Response Protein Transport IRE1-mediated Unfolded Protein Response Transmembrane Transport Cerebellar Purkinje Cell Layer Development Protein Folding In Endoplasmic Reticulum Positive Regulation Of Transcription By RNA Polymerase II Intracellular Transport Proteolysis Negative Regulation Of IRE1-mediated Unfolded Protein Response Somite Specification Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Sec61 Translocon Complex SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Establishment Of Protein Localization Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Misfolded Protein Binding Segment Specification Somite Development Cotranslational Protein Targeting To Membrane Negative Regulation Of Glial Cell Proliferation Retrograde Protein Transport, ER To Cytosol Anatomical Structure Arrangement
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?