MAP6 and RARB

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
HPRD (two hybrid)

		MAP6	RARB
Gene Name		microtubule-associated protein 6	retinoic acid receptor, beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Microtubule Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Calmodulin Binding Microtubule Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA Binding Steroid Hormone Receptor Activity Retinoic Acid Receptor Activity Protein Binding Drug Binding Zinc Ion Binding Protein Complex Binding Retinoid X Receptor Binding
	Biological Process	Microtubule Cytoskeleton Organization Transport Lysosome Localization Dendrite Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ureteric Bud Development Glandular Epithelial Cell Development Outflow Tract Septum Morphogenesis Retinal Pigment Epithelium Development Growth Plate Cartilage Development Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Gene Expression Striatum Development Regulation Of Myelination Negative Regulation Of Chondrocyte Differentiation Embryonic Hindlimb Morphogenesis Multicellular Organism Growth Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Eye Morphogenesis Retinoic Acid Receptor Signaling Pathway Embryonic Digestive Tract Development Ventricular Cardiac Muscle Cell Differentiation Transmembrane Transport
Pathways			Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters
Drugs			Adapalene Acitretin Alitretinoin Tazarotene Etretinate TTNPB Tamibarotene
Diseases
GWAS			Airflow obstruction ( 22837378) Obesity (extreme) ( 19553259) Pulmonary function ( 21946350) Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		6 interactors: NR2F1 RARB RARG RORB TRAF1 TUBB	19 interactors: CCNH CEBPA CEBPB EIF3I GATA3 HR MAP6 MEOX2 NCOA1 NCOA3 NCOR2 NR4A2 PNRC1 PRKD2 RXRA RXRB RXRG SMAD2 SRC
Entrez ID		4135	5915
HPRD ID		15989	07183
Ensembl ID		ENSG00000171533	ENSG00000077092
Uniprot IDs		Q6ZWB8 Q96JE9	F1D8S6 P10826 Q5QHG3
PDB IDs			1HRA 1XAP 4DM6 4DM8
Enriched GO Terms of Interacting Partners?		Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Retinal Pigment Epithelium Development Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Cellular Response To Hormone Stimulus Eye Morphogenesis Retina Development In Camera-type Eye Growth Plate Cartilage Development Negative Regulation Of Cell Differentiation Negative Regulation Of Chondrocyte Differentiation Retinoic Acid Receptor Signaling Pathway Endochondral Bone Growth Glandular Epithelial Cell Development Response To Lipid Negative Regulation Of Cartilage Development Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Cartilage Development Involved In Endochondral Bone Morphogenesis Response To Hormone Embryonic Eye Morphogenesis Columnar/cuboidal Epithelial Cell Development Glandular Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Myelination Embryonic Hindlimb Morphogenesis Camera-type Eye Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Hindlimb Morphogenesis Eye Development Cellular Response To Retinoic Acid Regulation Of Chondrocyte Differentiation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Endochondral Bone Morphogenesis Regulation Of Cartilage Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Organ Growth Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Sensory Organ Development Multicellular Organism Growth	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Response To Lipid Regulation Of Gene Expression Gene Expression Regulation Of Transcription, DNA-templated Response To Steroid Hormone Regulation Of Nucleic Acid-templated Transcription Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process In Utero Embryonic Development Macromolecule Biosynthetic Process Cellular Response To Organic Substance Chordate Embryonic Development Intracellular Receptor Signaling Pathway Embryo Development Ending In Birth Or Egg Hatching RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Initiation Regulation Of Nitrogen Compound Metabolic Process Response To Organic Cyclic Compound Response To Hormone Gland Development Reproductive Structure Development Reproductive System Development Response To Organic Substance Embryo Development Biosynthetic Process Placenta Development System Development Positive Regulation Of Metabolic Process Tissue Development Regulation Of Metabolic Process Cellular Response To Organic Cyclic Compound Organ Development Nucleobase-containing Compound Metabolic Process Developmental Process Involved In Reproduction Epithelium Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		al als amyotrophic become combine degeneration embo frontotemporal ftld genetically issue journal lateral live lobar lysosomal partner pathologies pathology played priority proteomics schwenk sclerosis tdp tmem106b uncovering unveil variants	activating backcross chromosomes contain cosegregated enhancers fragment homology interspecific loci mapped mchr mediate none rara rarg reports responsive restriction retinoic retinoid rflvs rxr subclass syntenic terms trans variants
Tagcloud (Difference) ?		al als amyotrophic become combine degeneration embo frontotemporal ftld genetically issue journal lateral live lobar lysosomal partner pathologies pathology played priority proteomics schwenk sclerosis tdp tmem106b uncovering unveil	activating backcross chromosomes contain cosegregated enhancers fragment homology interspecific loci mapped mchr mediate none rara rarg reports responsive restriction retinoic retinoid rflvs rxr subclass syntenic terms trans
Tagcloud (Intersection) ?		variants