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ELOB and ZYG11B
Number of citations of the paper that reports this interaction (PubMedID
31253590
)
89
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
ELOB
ZYG11B
Description
elongin B
zyg-11 family member B, cell cycle regulator
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
VCB Complex
Cul2-RING Ubiquitin Ligase Complex
Cul5-RING Ubiquitin Ligase Complex
Elongin Complex
Cytoplasm
Cul2-RING Ubiquitin Ligase Complex
Molecular Function
Transcription Corepressor Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Protein Binding
Biological Process
Transcription Initiation At RNA Polymerase II Promoter
Transcription Elongation By RNA Polymerase II
Protein Ubiquitination
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein-containing Complex Assembly
Target-directed MiRNA Degradation
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Formation of RNA Pol II elongation complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Vif-mediated degradation of APOBEC3G
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Neddylation
Regulation of expression of SLITs and ROBOs
Inactivation of CSF3 (G-CSF) signaling
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
Evasion by RSV of host interferon responses
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
Diseases
GWAS
Monocyte percentage of white cells (
32888494
)
Interacting Genes
23 interacting genes:
ASB11
ASB2
ASB8
BRD4
CEBPA
CEBPE
ELOA
ELOA2
ELOA3P
ELOC
EPOR
GHR
GPS1
LRRC41
MRPL53
PRAME
RACK1
RBX1
SOCS1
SOCS3
SOCS6
VHL
ZYG11B
4 interacting genes:
CUL2
ELOB
ELOC
GBF1
Entrez ID
6923
79699
HPRD ID
02874
13356
Ensembl ID
ENSG00000103363
ENSG00000162378
Uniprot IDs
A0A384MDL3
Q15370
A8DPD7
B4DK95
Q9C0D3
PDB IDs
1LM8
1LQB
1VCB
2C9W
2IZV
2JZ3
2MA9
3DCG
3ZKJ
3ZNG
3ZRC
3ZRF
3ZTC
3ZTD
3ZUN
4AJY
4AWJ
4B95
4B9K
4BKS
4BKT
4N9F
4W9C
4W9D
4W9E
4W9F
4W9G
4W9H
4W9I
4W9J
4W9K
4W9L
4WQO
5BO4
5LLI
5N4W
5NVV
5NVW
5NVX
5NVY
5NVZ
5NW0
5NW1
5NW2
5T35
6BVB
6C5X
6FMI
6FMJ
6FMK
6GFX
6GFY
6GFZ
6GMN
6GMQ
6GMR
6GMX
6HAX
6HAY
6HR2
6I4X
6I5J
6I5N
6I7Q
6I7R
6P59
6R6H
6R7F
6R7H
6R7I
6R7N
6SIS
6V9H
6ZHC
7CJB
7JTO
7JTP
7KHH
7M6T
7PI4
7PLO
7Q2J
7S4E
7UPN
7Z6L
7Z76
7Z77
7ZLM
7ZLN
7ZLO
7ZLP
7ZLR
7ZLS
7ZNT
8BB2
8BB3
8BB4
8BB5
8BDI
8BDJ
8BDL
8BDM
8BDN
8BDO
8BDS
8BDT
8BDX
8BEB
8C13
8CQE
8CQK
8CQL
8CX0
8CX1
8CX2
8EBN
8EI3
8EWV
8FVI
8FVJ
8FY0
8FY1
8FY2
8G1P
8G1Q
8IJ1
8JAL
8JAQ
8JAR
8JAS
8JAU
8JAV
8JE1
8JE2
8OEV
8OEW
8OF0
8OKX
8OL1
8P0F
8PC2
8PQL
8Q7R
8QJR
8QJS
8QU8
8QVU
8QW6
8QW7
8R5H
8RWZ
8RX0
8SH2
8SZK
8VL9
8VLB
8WDK
8WQA
8WQB
8WQC
8WQE
8WQF
8WQG
8WQH
8Y1U
8YMB
8ZV8
8ZVJ
9BJU
9BOL
9D1I
9D1Y
9D1Z
9D8P
9EQJ
9EQM
9IPW
7EP0
7EP1
7EP2
7XV7
7XYV
7XYW
7XYX
7YC2
Enriched GO Terms of Interacting Partners
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Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein Metabolic Process
Elongin Complex
Proteolysis Involved In Protein Catabolic Process
Cul2-RING Ubiquitin Ligase Complex
Protein Modification Process
Macromolecule Metabolic Process
Macromolecule Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis
Proteasomal Protein Catabolic Process
Cul5-RING Ubiquitin Ligase Complex
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
Regulation Of Receptor Signaling Pathway Via JAK-STAT
VCB Complex
Cell Surface Receptor Signaling Pathway Via STAT
Protein Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Receptor Signaling Pathway Via STAT
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Intracellular Signal Transduction
Macrophage Differentiation
Transcription Elongation By RNA Polymerase II
Protein Tyrosine Kinase Inhibitor Activity
Negative Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Cellular Response To Insulin Stimulus
Cytokine-mediated Signaling Pathway
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
DNA-templated Transcription Elongation
Negative Regulation Of Signal Transduction
GTPase Inhibitor Activity
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Insulin Receptor Signaling Pathway
Interleukin-6-mediated Signaling Pathway
Regulation Of Cellular Response To Insulin Stimulus
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Catabolic Process
Centrosome Duplication
Cul2-RING Ubiquitin Ligase Complex
Target-directed MiRNA Degradation
Elongin Complex
Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA
Negative Regulation Of MiRNA-mediated Gene Silencing
MiRNA Catabolic Process
Cul5-RING Ubiquitin Ligase Complex
MiRNA Metabolic Process
Regulation Of Post-transcriptional Gene Silencing
Regulation Of MiRNA-mediated Gene Silencing
Aspartoacylase Activity
Protein-macromolecule Adaptor Activity
Transcription Corepressor Binding
Transcription Initiation At RNA Polymerase II Promoter
Protein Localization To Endoplasmic Reticulum Tubular Network
Diacyl Lipopeptide Binding
Nuclear Pore Transmembrane Ring
Actin Polymerization Or Depolymerization
Cell Leading Edge
Actin Cytoskeleton
Golgi Apparatus Subcompartment
Endoplasmic Reticulum-Golgi Intermediate Compartment Organization
Toll-like Receptor 2-Toll-like Receptor 6 Protein Complex
Detection Of Diacyl Bacterial Lipopeptide
DNA-templated Transcription Initiation
Acetate Metabolic Process
Cytosol
VCB Complex
CTP Salvage
Muscle Cell Projection Membrane
Actin Filament Fragmentation
Cytidine Kinase Activity
Uridine Kinase Activity
CMP Biosynthetic Process
Endomembrane System Organization
Toll-like Receptor 2 Binding
Detection Of Bacterial Lipoprotein
Toll-like Receptor TLR6:TLR2 Signaling Pathway
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Tagcloud (Intersection)
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