ZYG11B

Description		zyg-11 family member B, cell cycle regulator
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GO Annotations	Cellular Component	Cytoplasm Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494)
Novel Interacting Genes		10 novel interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 NDC1 OSBPL9 SH2D2A TLR6 UCK2
Interacting Genes		4 interacting genes: CUL2 ELOB ELOC GBF1
Entrez ID		79699
HPRD ID		13356
Ensembl ID		ENSG00000162378
Uniprot IDs		A8DPD7 B4DK95 Q9C0D3
PDB IDs		7EP0 7EP1 7EP2 7XV7 7XYV 7XYW 7XYX 7YC2
Enriched GO Terms of Interacting Partners?		Cul2-RING Ubiquitin Ligase Complex Target-directed MiRNA Degradation Elongin Complex Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Negative Regulation Of MiRNA-mediated Gene Silencing MiRNA Catabolic Process Cul5-RING Ubiquitin Ligase Complex MiRNA Metabolic Process Regulation Of Post-transcriptional Gene Silencing Regulation Of MiRNA-mediated Gene Silencing Aspartoacylase Activity Protein-macromolecule Adaptor Activity Transcription Corepressor Binding Transcription Initiation At RNA Polymerase II Promoter Protein Localization To Endoplasmic Reticulum Tubular Network Diacyl Lipopeptide Binding Nuclear Pore Transmembrane Ring Actin Polymerization Or Depolymerization Cell Leading Edge Actin Cytoskeleton Golgi Apparatus Subcompartment Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Toll-like Receptor 2-Toll-like Receptor 6 Protein Complex Detection Of Diacyl Bacterial Lipopeptide DNA-templated Transcription Initiation Acetate Metabolic Process Cytosol VCB Complex CTP Salvage Muscle Cell Projection Membrane Actin Filament Fragmentation Cytidine Kinase Activity Uridine Kinase Activity CMP Biosynthetic Process Endomembrane System Organization Toll-like Receptor 2 Binding Detection Of Bacterial Lipoprotein Toll-like Receptor TLR6:TLR2 Signaling Pathway
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