TARS and C7orf25

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TARS	C7orf25
Gene Name		threonyl-tRNA synthetase	chromosome 7 open reading frame 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Threonine-tRNA Ligase Activity ATP Binding Protein Homodimerization Activity
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Threonyl-tRNA Aminoacylation Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Threonine
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BRCA1 C7orf25 HARS NDRG1 TARSL2	18 interactors: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 HAP1 HEXDC MTOR NGEF PTN RASSF1 RPL36AL SF3B2 TARS UBE2D1
Entrez ID		6897	79020
HPRD ID		01762	09861
Ensembl ID		ENSG00000113407	ENSG00000136197
Uniprot IDs		P26639	Q9BPX7
PDB IDs		1WWT 4HWT
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Carboxylic Acid Metabolic Process Positive Regulation Of Histone H3-K9 Acetylation Histidyl-tRNA Aminoacylation Organic Acid Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Cell Cycle Process TRNA Metabolic Process Threonyl-tRNA Aminoacylation Cellular Response To Indole-3-methanol Positive Regulation Of Cell Cycle Negative Regulation Of Centriole Replication Positive Regulation Of Spindle Checkpoint Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Positive Regulation Of Cell Cycle Checkpoint Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Cellular Amino Acid Metabolic Process NcRNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Peripheral Nervous System Myelin Maintenance Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Small Molecule Metabolic Process Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter	Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Stress Regulation Of Intracellular Signal Transduction Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Protein Catabolic Process Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Cellular Component Organization Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Differentiation Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Cell Projection Organization Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Protein Modification Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Differentiation Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Division Positive Regulation Of Neurotrophin Production Regulation Of Carbohydrate Utilization Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		bed biosolids c6h6 calibrated ch4 char co2 devolatilization disposal drying equivalence fluidized fuel gaseous gases gasification gasifier gasifiers h2 h2o land mathematical offering recover reserved sewage sludge syngas unburned
Tagcloud (Difference) ?		bed biosolids c6h6 calibrated ch4 char co2 devolatilization disposal drying equivalence fluidized fuel gaseous gases gasification gasifier gasifiers h2 h2o land mathematical offering recover reserved sewage sludge syngas unburned
Tagcloud (Intersection) ?