TARS1 and C7orf25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TARS1	C7orf25
Description		threonyl-tRNA synthetase 1	chromosome 7 open reading frame 25
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Aminoacyl-tRNA Ligase Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Zinc Ion Binding Ligase Activity Identical Protein Binding	Protein Binding
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Threonyl-tRNA Aminoacylation TRNA Aminoacylation
Pathways		Cytosolic tRNA aminoacylation
Drugs		Threonine
Diseases
GWAS			Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)
Interacting Genes		9 interacting genes: BRCA1 C7orf25 CEBPA DSCR9 HARS1 HSPB1 LINC01554 NDRG1 RNF10	20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1
Entrez ID		6897	79020
HPRD ID		01762	09861
Ensembl ID		ENSG00000113407	ENSG00000136197
Uniprot IDs		P26639	Q9BPX7
PDB IDs		1WWT 4HWT 4P3N 4TTV 5XLN
Enriched GO Terms of Interacting Partners?			Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Projection Organization Regulation Of Protein Metabolic Process Positive Regulation Of Dendrite Development Regulation Of Cell Projection Organization Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Metabolic Process Regulation Of Gliogenesis Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Ubiquitination Cytoplasmic Translation Ephrin Receptor Binding Positive Regulation Of Post-translational Protein Modification Delta1-piperideine-2-carboxylate Reductase Activity Nucleus Thiomorpholine-carboxylate Dehydrogenase Activity Regulation Of Cellular Component Organization Positive Regulation Of Neuron Projection Development Positive Regulation Of Protein Modification Process Hepatocyte Homeostasis Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Modification Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Neurogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Translation Transmembrane Transporter Binding Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Glial Cell Differentiation Regulation Of Protein Catabolic Process Pyrimidine-containing Compound Biosynthetic Process Regulation Of Oligodendrocyte Differentiation Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Cellular Response To Glycine Response To Singlet Oxygen Positive Regulation Of Neurotrophin Production Histone H4K8ac Reader Activity Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Myelination T Cell Costimulation Regulation Of Cell Cycle Process Regulation Of Neuron Projection Development Cellular Response To Stress Regulation Of Nervous System Development Positive Regulation Of Cell Development Dendrite Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
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