TARS

Gene Name		threonyl-tRNA synthetase
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Threonine-tRNA Ligase Activity ATP Binding Protein Homodimerization Activity
	Biological Process	Translation TRNA Aminoacylation For Protein Translation Threonyl-tRNA Aminoacylation Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Threonine
Diseases
GWAS
Protein-protein Interactions		5 interactors: BRCA1 C7orf25 HARS NDRG1 TARSL2
Entrez ID		6897
HPRD ID		01762
Ensembl ID		ENSG00000113407
Uniprot IDs		P26639
PDB IDs		1WWT 4HWT
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Carboxylic Acid Metabolic Process Positive Regulation Of Histone H3-K9 Acetylation Histidyl-tRNA Aminoacylation Organic Acid Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Cell Cycle Process TRNA Metabolic Process Threonyl-tRNA Aminoacylation Cellular Response To Indole-3-methanol Positive Regulation Of Cell Cycle Negative Regulation Of Centriole Replication Positive Regulation Of Spindle Checkpoint Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Positive Regulation Of Cell Cycle Checkpoint Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Cellular Amino Acid Metabolic Process NcRNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Peripheral Nervous System Myelin Maintenance Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Small Molecule Metabolic Process Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter
Tagcloud ?		bed biosolids c6h6 calibrated ch4 char co2 devolatilization disposal drying equivalence fluidized fuel gaseous gases gasification gasifier gasifiers h2 h2o land mathematical offering recover reserved sewage sludge syngas unburned