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TAP2 and PSMG3
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
TAP2
PSMG3
Gene Name
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
proteasome (prosome, macropain) assembly chaperone 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Endoplasmic Reticulum Membrane
TAP Complex
Molecular Function
Transporter Activity
Protein Binding
ATP Binding
Peptide Transporter Activity
Peptide Antigen-transporting ATPase Activity
MHC Class Ib Protein Binding
TAP1 Binding
Tapasin Binding
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-dependent
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Via ER Pathway, TAP-dependent
Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Metabolic Process
Intracellular Transport Of Viral Protein In Host Cell
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Cytosol To ER Transport
Peptide Antigen Transport
Transmembrane Transport
Pathways
Class I MHC mediated antigen processing & presentation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing-Cross presentation
ER-Phagosome pathway
Adaptive Immune System
Drugs
Diseases
GWAS
Lymphoma (
23349640
)
Nephropathy (
21399633
)
Pubertal anthropometrics (
23449627
)
Protein-Protein Interactions
9 interactors:
APP
HLA-C
HLA-G
PSMB5
PSMB8
PSMG3
RBM18
TAP1
TAPBP
5 interactors:
PSMB1
PSMB3
PSMB4
PSMB5
TAP2
Entrez ID
6891
84262
HPRD ID
01360
14404
Ensembl ID
ENSG00000204267
ENSG00000157778
Uniprot IDs
Q03519
Q9UP03
Q9BT73
PDB IDs
2Z5E
Enriched GO Terms of Interacting Partners
?
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen
Antigen Processing And Presentation
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Endogenous Antigen
Immune System Process
Type I Interferon Signaling Pathway
Cellular Response To Type I Interferon
Response To Type I Interferon
Viral Process
Immune Response
Defense Response
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Innate Immune Response
Positive Regulation Of Cell Cycle
Response To Stress
Positive Regulation Of Proteolysis
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Mitotic Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of T Cell Mediated Cytotoxicity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Cytokine-mediated Signaling Pathway
Positive Regulation Of Ligase Activity
Regulation Of T Cell Mediated Cytotoxicity
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Regulation Of Cell Cycle Process
Regulation Of Ubiquitin-protein Transferase Activity
Peptide Antigen Stabilization
Regulation Of Cellular Ketone Metabolic Process
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Antigen Processing And Presentation Of Peptide Antigen
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Antigen Processing And Presentation
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Protein Ubiquitination
Signal Transduction By P53 Class Mediator
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Viral Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Cellular Protein Catabolic Process
DNA Damage Checkpoint
Positive Regulation Of Wnt Signaling Pathway
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Checkpoint
Protein Polyubiquitination
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Tagcloud
?
beta2
blocker
chains
clamp
class
confocal
detectable
dissociated
drastically
electric
electrophysiological
electrophysiology
exceptions
heavy
ifn
mhc
microglobulin
neurons
neurotransmitter
partly
patch
reverted
tap1
tetrodotoxin
transcribe
transcribed
transporters
upregulate
Tagcloud (Difference)
?
beta2
blocker
chains
clamp
class
confocal
detectable
dissociated
drastically
electric
electrophysiological
electrophysiology
exceptions
heavy
ifn
mhc
microglobulin
neurons
neurotransmitter
partly
patch
reverted
tap1
tetrodotoxin
transcribe
transcribed
transporters
upregulate
Tagcloud (Intersection)
?